Results 221 to 230 of about 41,053 (237)

Ganglioside deficiency in hypothalamic POMC neurons promotes body weight gain

International Journal of Obesity, 2019
Glucosylceramide synthase (GCS; gene: UDP-glucose:ceramide glucosyltransferase (Ugcg))-derived gangliosides comprise a specific class of lipids in the plasma membrane that modulate the activity of transmembrane receptors. GCS deletion in hypothalamic arcuate nucleus (Arc) neurons leads to prominent obesity.
V. Dieterle, S. Herzer, H.-J. Gröne, R. Jennemann, V. Nordström   +4 more
openaire   +2 more sources

Appetite-inducing accumbens manipulation activates hypothalamic orexin neurons and inhibits POMC neurons

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2003
Corticolimbic circuits involving the prefrontal cortex, amygdala, and ventral striatum determine the reward value of food and might play a role in environmentally induced obesity. Chemical manipulation of the nucleus accumbens shell (AcbSh) has been shown to elicit robust feeding and Fos expression in the hypothalamus and other brain areas of satiated
Huiyuan Zheng, Michele Corkern, Irina Stoyanova, Laurel M. Patterson, Rui Tian, Hans-Rudolf Berthoud   +5 more
openaire   +1 more source

Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis

Cell Metabolism, 2021
Macarena Pozo Ariza, Luis Varela, Sara Ramirez Flores   +2 more
exaly  

Insulinwirkung auf AgRP- und POMC-Neurone

Diabetologie und Stoffwechsel, 2017
openaire   +1 more source

Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity

Nature, 2007
Roberto Coppari, Pablo J Enriori, Chen-Yu Zhang   +2 more
exaly  

Simultaneous targeting of POMC and AgRP neurons

Nature Metabolism
openaire   +2 more sources

Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat

Cell, 2015
Garron T Dodd, Kim Loh, Stephanie E Simonds   +2 more
exaly  

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

Nature, 2001
Michael A Cowley, Marcelo Rubinstein, Sabrina Diano   +2 more
exaly  

Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis

Cell Metabolism, 2014
Tiemin Liu, Xingxing Kong, Makoto Fukuda
exaly  

Leptin-Dependent Control of Glucose Balance and Locomotor Activity by POMC Neurons

Cell Metabolism, 2009
Kevin M Gamber, Nicholas Huntoon
exaly