Results 71 to 80 of about 320,389 (303)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Temporary ponds in the UK; a critical biodiversity resource for freshwater plants and animals [PDF]
, 2001 The importance of ponds for biodiversity in Britain has been demonstrated by a number of studies. However, most of the research and interest has been directed at permanent waterbodies, and temporary ponds have been largely neglected.
Nicolet, Pascal
core
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Water Resources ResearchWith the goal of eradication by 2030, Malaria poses a significant health threat, profoundly influenced by meteorological and hydrological conditions. In support of malaria vector control efforts, we present a high‐resolution, coupled physically‐based ...
Mame Diarra Bousso Dieng +11 more
doaj +1 more source
Poverty alleviation among fishermen within the floodplains of Kaduna River: implication for introducing commercial fish farming at village level in Doko local government area of Niger State, Nigeria [PDF]
, 2005 A diagnostic survey was conducted among the fishermen in six selected villages in Doko Local Government Area of Niger State. One hundred and fifty fishermen were randomly selected and interviewed to find out whether or not they had interest in commercial
Gana, F.S., Yaro, I.
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A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
EcosphereFreshwater ponds host diverse arthropod communities, but conservation frameworks are scarce. Heterogeneous pond mosaics of various sizes and successional stages can develop during raw material extraction in mining sites, acting as refugia for a variety ...
Vera Zizka +4 more
doaj +1 more source
Diversity of lakes and ponds in the forest-tundra ecozone: from limnicity to limnodiversity
GIScience & Remote SensingArctic and subarctic landscapes have unique hydrological and limnological features and are now experiencing rapid change due to climate warming and permafrost thaw. The highly abundant lakes, ponds, and rivers across these landscapes play an increasingly
Pedro Freitas +8 more
doaj +1 more source
Using full-scale duckweed ponds as the finish stage for swine waste treatment with a focus on organic matter degradation [PDF]
, 2014 Artigo Publicado em: IWA - Water Science & TechnologyThe rapid increase in the number of swine has caused pronounced environmental impacts worldwide, especially on water resources.
Belli Filho, Paulo +3 more
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source