UNITED: A Unified Transparent and Efficient Phase I/II Trial Design for Dose Optimization Accounting for Ordinal Graded, Continuous and Mixed Toxicity and Efficacy Endpoints. [PDF]
Li M, Guo Z, Qiu Y.
europepmc +1 more source
Reconstructing time-to-event data from published Kaplan-Meier curves. [PDF]
Wei Y, Royston P.
europepmc +1 more source
Graph‐based imitation and reinforcement learning for efficient Benders decomposition
Abstract This work introduces an end‐to‐end graph‐based agent for accelerating the computational efficiency of Benders Decomposition. The agent's policy is parameterized by a graph neural network, which takes as input a bipartite graph representation of the master problem and proposes a candidate solution.
Bernard T. Agyeman +3 more
wiley +1 more source
DepthPark is a cost‐effective indoor parking management system that uses monocular cameras, two fixed cameras, and one mobile camera per parking lane, together with deep learning. By combining license plate recognition, parking‐slot classification, and single‐frame depth estimation, the system enables real‐time occupancy monitoring and parking ...
Lakshay Naresh Ramchandani +1 more
wiley +1 more source
Comb-BOIN12: A Utility-Based Bayesian Optimal Interval Design for Dose Optimization in Cancer Drug-Combination Trials. [PDF]
Lu M, Zhang J, Yuan Y, Lin R.
europepmc +1 more source
Causal Effect Estimation With TMLE: Handling Missing Data and Near Violations of Positivity
ABSTRACT We evaluate the performance of targeted maximum likelihood estimation (TMLE) for estimating the average treatment effect in missing data scenarios under varying levels of positivity violations. We employ model‐ and design‐based simulations, with the latter using undersmoothed highly adaptive lasso on the “WASH Benefits Bangladesh” data set to ...
Christoph Wiederkehr +2 more
wiley +1 more source
Scenario‐Based Platoon Lane Network Design
ABSTRACT A truck platoon is a set of trucks that drive behind one another at short headways to save fuel, reduce emissions, and improve traffic throughput. Despite the potential benefits of platooning, road operators have raised concerns about the impact of platoons on surrounding traffic.
Anirudh Kishore Bhoopalam +2 more
wiley +1 more source
ABSTRACT This study investigates the impact mechanism of different dimensions of failure learning on corporate innovation performance. Compared with the extensively researched field in the effects of organizational failure learning, this area remains largely underexplored.
Shiyuan Zhou, Yichao Si
wiley +1 more source
A phase 1b study of the ERK inhibitor MK-8353 plus pembrolizumab in patients with advanced solid tumors. [PDF]
Lakhani NJ +5 more
europepmc +1 more source
A Probabilistic Greedy Attempt to Be Fair in Neural Team Recommendation
ABSTRACT Neural team recommendation has brought state‐of‐the‐art efficacy while enhancing efficiency at forming teams of experts whose success in completing complex tasks is almost surely guaranteed. However, they overlook fairness, that is, predicted teams are heavily biased toward popular and male experts, falling short of recommending female or ...
Hamed Loghmani +4 more
wiley +1 more source

