Advanced Materials, EarlyView.Intrinsically disordered protein‐inspired nanovectors (IDP‐NVs) form stable nanocoacervates (NCs) with diverse biomacromolecules. In situ conformational changes confer stability and adaptability to NCs under dynamically changing physiological conditions.
Soyeong Jin +14 more
wiley +1 more source
Recent advances in delivery systems and therapeutics of cinnarizine: a poorly water soluble drug with absorption window in stomach. [PDF]
J Drug Deliv, 2014 Raghuvanshi S, Pathak K.
europepmc +1 more source
Oral nanomedicines for the treatment of parasitic diseases [PDF]
, 2014 Dea Ayuela, Maria Auxiliadora +3 more
core +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Critical material attributes (CMAs) of strip films loaded with poorly water-soluble drug nanoparticles: I. Impact of plasticizer on film properties and dissolution. [PDF]
Eur J Pharm Sci, 2016 Krull SM +4 more
europepmc +1 more source
Advanced Materials, EarlyView.A PVA‐based macromolecular thiol‐ene formulation enables efficient two‐photon polymerization at extremely low polymer concentrations and high writing speeds of 400 mm s−1 (20×), allowing high‐fidelity laser writing of cell‐interactive hydrogel structures on demand.
Wanwan Qiu +6 more
wiley +1 more source
Novel in situ self-assembly nanoparticles for formulating a poorly water-soluble drug in oral solid granules, improving stability, palatability, and bioavailability. [PDF]
Int J Nanomedicine, 2016 Guo S, Pham K, Li D, Penzak SR, Dong X.
europepmc +1 more source
Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics
Advanced Materials, EarlyView.This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang +13 more
wiley +1 more source
From bench to humans: formulation development of a poorly water soluble drug to mitigate food effect. [PDF]
AAPS PharmSciTech, 2014 Pandey P +9 more
europepmc +1 more source
Advanced Materials, EarlyView.The water permeability of amorphous carbon dots (CDs) is demonstrated by investigating their plasticization. Novel polyamide‐based and amorphous nanoparticles are synthesized by controlling their inner packing density. Water plasticization is evidenced by the decrease of the CDs glass transition temperature with increasing the hydration degree.
Elisa Sturabotti +8 more
wiley +1 more source