Results 51 to 60 of about 6,918,483 (191)

The Missing Link of Jewish European Ancestry: Contrasting the Rhineland and the Khazarian Hypotheses [PDF]

, 2012
The question of Jewish ancestry has been the subject of controversy for over two centuries and has yet to be resolved. The "Rhineland Hypothesis" proposes that Eastern European Jews emerged from a small group of German Jews who migrated eastward and ...
Alexander, Atzmon, Balanovsky, Baron, Behar, Behar, Bonné-Tamir, Brook, Browning, Carmeli, Chakravarti, Conrad, Dinur, Dvornik, Eran Elhaik, Excoffier, Finkelstein, Gilbert, Hammer, Hitti, Koestler, Kopelman, Levy-Coffman, Li, McVean, Nebel, Novembre, Ostrer, Ostrer, Pagani, Patai, Patterson, Payaslian, Pickrell, Polak, Price, Price, Purcell, Reich, Sand, Schonberg, Shapira, Shlush, Straten, Straten, Tian, Weiss, Wexler, Zoossmann-Diskin   +48 more
core   +2 more sources

Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates. [PDF]

, 2020
Current evidence from case/control studies indicates that genetic risk for psychiatric disorders derives primarily from numerous common variants, each with a small phenotypic impact. The literature describing apparent segregation of bipolar disorder (BP)
Aldana, Ileana, Araya, Carmen, Araya, Xinia, Bearden, Carrie E, Bedoya, Gabriel, Bejarano, Julio, Cantor, Rita M, Castrillón, Gabriel, Coppola, Giovanni, Escobar, Javier I, Fears, Scott C, Freimer, Nelson B, Gomez-Makhinson, Juliana, Huang, Alden Y, Hwang, Sun-Goo, Kremeyer, Barbara, Lopez, Maria C, Lopez-Jaramillo, Carlos, Macaya, Gabriel, Molina, Julio, Montoya, Claudia P, Montoya, Gabriel, Mullins, Niamh, Olde Loohuis, Loes M, Ophoff, Roel A, Ori, Anil PS, Ospina-Duque, Jorge, Park, YoungJun, Ramensky, Vasily, Ramirez, Margarita, Reus, Victor, Ruiz-Linares, Andres, Sabatti, Chiara, Service, Susan K, Spesny, Mitzi, Sul, Jae Hoon, Teshiba, Terri M, Zhang, Zhongyang   +37 more
core   +3 more sources

Admixture, Population Structure, and F-Statistics [PDF]

Genetics, 2015
Abstract Many questions about human genetic history can be addressed by examining the patterns of shared genetic variation between sets of populations. A useful methodological framework for this purpose is F-statistics that measure shared genetic drift between sets of two, three, and four populations and can be used to test simple and ...
openaire   +3 more sources

Genome-wide analysis of unrecognised ethnic group Chuanqing people revealing a close affinity with Southern Han Chinese

Annals of Human Biology, 2020
Background Chuanqing is an unrecognised ethnic group in Guizhou, southwest China. The genetic history of the Chuanqing people is hotly debated due to a lack of available genetic data.
Jiani Lu, Hongling Zhang, Zheng Ren, Qiyan Wang, Yubo Liu, Yingxiang Li, Guanglin He, Jianxin Guo, Jing Zhao, Rong Hu, Lan-Hai Wei, Gang Chen, Jiang Huang, Chuan‑Chao Wang   +13 more
doaj   +1 more source

2BAD: an application to estimate the parental contributions during two independent admixture events [PDF]

, 2010
Several approaches have been developed to calculate the relative contributions of parental populations in single admixture event scenarios, including Bayesian methods.
B. PARREIRA, Beaumont MA, Beaumont MA, Chikhi L, L. CHIKHI, M. W. BRUFORD, T. C. BRAY, V. C. SOUSA, Wang J   +8 more
core   +1 more source

Exploring Population Structure with Admixture Models and Principal Component Analysis.

Methods in molecular biology, 2020
Population structure is a commonplace feature of genetic variation data, and it has importance in numerous application areas, including evolutionary genetics, conservation genetics, and human genetics. Understanding the structure in a sample is necessary
Chi-Chun Liu, S. Shringarpure, K. Lange, J. Novembre   +3 more
semanticscholar   +1 more source

Gene Admixture in the Costa Rican Population

Annals of Human Genetics, 2003
SummaryThe general population of Costa Rica has sometimes been considered to be the product of an amalgamation of groups of diverse origin. To determine the magnitude of accumulated admixture since Spanish colonization, 11 classic genetic markers were analyzed in a total of 2196 individuals originating from five distinct regions of the country.
Morera Brenes, Bernal, Barrantes Mesén, Ramiro, Marín Rojas, Rafael   +2 more
openaire   +3 more sources

AdFiT v1.7 (Admixture Files Tool): input files creating tool for population genetic admixture estimation software

Bulletins et Mémoires de la Société d’Anthropologie de Paris, 2009
The six most commonly used software programs in the literature for population genetic admixture estimation since 20 years, are ADMIX, ADMIX95, Mistura, Admix 2.0, LEA, and LEADMIX, and each one has its own specific file format and filename extensions. We
Géraud Gourjon, Anna Degioanni
doaj   +1 more source

Neural ADMIXTURE: rapid population clustering with autoencoders [PDF]

, 2021
ABSTRACTCharacterizing the genetic substructure of large cohorts has become increasingly important as genetic association and prediction studies are extended to massive, increasingly diverse, biobanks. ADMIXTURE and STRUCTURE are widely used unsupervised clustering algorithms for characterizing such ancestral genetic structure.
Albert Dominguez Mantes, Daniel Mas Montserrat, Carlos D. Bustamante, Xavier Giró-i-Nieto, Alexander G. Ioannidis   +4 more
openaire   +1 more source

Enhanced methods for local ancestry assignment in sequenced admixed individuals. [PDF]

, 2014
Inferring the ancestry at each locus in the genome of recently admixed individuals (e.g., Latino Americans) plays a major role in medical and population genetic inferences, ranging from finding disease-risk loci, to inferring recombination rates, to ...
Brown, Robert, Pasaniuc, Bogdan
core   +2 more sources