Results 61 to 70 of about 104,284 (184)

Genetic ancestry, admixture, and population structure in rural Dominica

PLOS ONE, 2021
The Caribbean is a genetically diverse region with heterogeneous admixture compositions influenced by local island ecologies, migrations, colonial conflicts, and demographic histories. The Commonwealth of Dominica is a mountainous island in the Lesser Antilles historically known to harbor communities with unique patterns of migration, mixture, and ...
Monica H. Keith, Mark V. Flinn, Harly J. Durbin, Troy N. Rowan, Gregory E. Blomquist, Kristen H. Taylor, Jeremy F. Taylor, Jared E. Decker   +7 more
openaire   +5 more sources

The potential for enhancing the power of genetic association studies in African Americans through the reuse of existing genotype data. [PDF]

PLoS Genetics, 2010
We consider the feasibility of reusing existing control data obtained in genetic association studies in order to reduce costs for new studies. We discuss controlling for the population differences between cases and controls that are implicit in studies ...
Gary K Chen, Robert C Millikan, Esther M John, Christine B Ambrosone, Leslie Bernstein, Wei Zheng, Jennifer J Hu, Stephen J Chanock, Regina G Ziegler, Elisa V Bandera, Brian E Henderson, Christopher A Haiman, Daniel O Stram   +12 more
doaj   +1 more source

The Missing Link of Jewish European Ancestry: Contrasting the Rhineland and the Khazarian Hypotheses [PDF]

, 2012
The question of Jewish ancestry has been the subject of controversy for over two centuries and has yet to be resolved. The "Rhineland Hypothesis" proposes that Eastern European Jews emerged from a small group of German Jews who migrated eastward and ...
Alexander, Atzmon, Balanovsky, Baron, Behar, Behar, Bonné-Tamir, Brook, Browning, Carmeli, Chakravarti, Conrad, Dinur, Dvornik, Eran Elhaik, Excoffier, Finkelstein, Gilbert, Hammer, Hitti, Koestler, Kopelman, Levy-Coffman, Li, McVean, Nebel, Novembre, Ostrer, Ostrer, Pagani, Patai, Patterson, Payaslian, Pickrell, Polak, Price, Price, Purcell, Reich, Sand, Schonberg, Shapira, Shlush, Straten, Straten, Tian, Weiss, Wexler, Zoossmann-Diskin   +48 more
core   +2 more sources

Relationship between adiposity and admixture in African-American and Hispanic-American women. [PDF]

, 2012
ObjectiveThe objective of this study was to investigate whether differences in admixture in African-American (AFA) and Hispanic-American (HA) adult women are associated with adiposity and adipose distribution.DesignThe proportion of European, sub-Saharan
Allison, M, Garcia, L, Kosoy, R, Manson, JE, Nassir, R, Ochs-Balcom, HM, Qi, L, Robbins, J, Seldin, MF, Shigeta, R, Tylavsky, F   +10 more
core  

Genome-wide SNP analysis of Southern African populations provides new insights into the dispersal of Bantu-speaking groups [PDF]

, 2015
The expansion of Bantu-speaking agropastoralist populations had a great impact on the genetic, linguistic, and cultural variation of sub-Saharan Africa. It is generally accepted that Bantu languages originated in an area around the present border between
ANAGNOSTOU, PAOLO, Busby, George B. J, Capelli, Cristian, DESTRO-BISOL, Giovanni, González Santos, Miguel, Montinaro, Francesco, Oosthuizen, Erica, Oosthuizen, Ockie, Pascali, Vincenzo   +8 more
core   +3 more sources

Inferring the ancestry of parents and grandparents from genetic data.

PLoS Computational Biology, 2020
Inference of admixture proportions is a classical statistical problem in population genetics. Standard methods implicitly assume that both parents of an individual have the same admixture fraction. However, this is rarely the case in real data.
Jingwen Pei, Yiming Zhang, Rasmus Nielsen, Yufeng Wu   +3 more
doaj   +1 more source

Admixture-enabled selection for rapid adaptive evolution in the Americas

Genome Biology, 2020
Background Admixture occurs when previously isolated populations come together and exchange genetic material. We hypothesize that admixture can enable rapid adaptive evolution in human populations by introducing novel genetic variants (haplotypes) at ...
Emily T. Norris, Lavanya Rishishwar, Aroon T. Chande, Andrew B. Conley, Kaixiong Ye, Augusto Valderrama-Aguirre, I. King Jordan   +6 more
doaj   +1 more source

Population genetics models of local ancestry

, 2012
Migrations have played an important role in shaping the genetic diversity of human populations. Understanding genomic data thus requires careful modeling of historical gene flow.
Falush, Li, Simon Gravel
core   +1 more source

The Genetic Structure and History of Africans and African Americans. [PDF]

, 2009
Africa is the source of all modern humans, but characterization of genetic variation and of relationships among populations across the continent has been enigmatic. We studied 121 African populations, four African American populations, and 60 non-African
A. A. Awomoyi, A. Froment, A. Ranciaro, A. T. Juma, Batini, Behar, Bereir, C. Ehret, C. Wambebe, Campbell, Cann, Cerny, Chen, Coia, Destro-Bisol, F. A. Reed, F. R. Friedlaender, Forster, Forster, Friedlaender, G. Lema, G. S. Pretorius, H. Mortensen, Hassan, J. B. Hirbo, J. H. Moore, J. L. Weber, J.-M. Bodo, Jakobsson, K. Powell, Li, Lind, M. A. Thera, M. Ibrahim, M. J. Kotze, M. W. Smith, O. Doumbo, Parra, Parra, Patin, Patterson, Pritchard, Pritchard, Reed, Reynolds, Rosenberg, Rosenberg, Rosenberg, S. A. Omar, S. A. Tishkoff, S. M. Williams, Salas, Scozzari, Semino, Sirugo, Smith, T. B. Nyambo, Tishkoff, Tishkoff, Verdu, Wang, Wood   +61 more
core   +1 more source

The footprint of recent and strong demographic decline in the genomes of Mangalitza pigs

Animal, 2019
The Mangalitza pig breed has suffered strong population reductions due to competition with more productive cosmopolitan breeds. In the current work, we aimed to investigate the effects of this sustained demographic recession on the genomic diversity of ...
V.A. Bâlteanu, T.F. Cardoso, M. Amills, I. Egerszegi, I. Anton, A. Beja-Pereira, A. Zsolnai   +6 more
doaj   +1 more source