Results 1 to 10 of about 4,860 (216)

Weight variability and cardiovascular outcomes: a systematic review and meta-analysis

Cardiovascular Diabetology, 2023
The association between body weight variability and the risk of cardiovascular disease (CVD) has been investigated previously with mixed findings. However, there has been no extensive study which systematically evaluates the current evidence. Furthermore,
Robert J. Massey, Moneeza K. Siddiqui, Ewan R. Pearson, Adem Y. Dawed   +3 more
doaj   +1 more source

Competing risks analysis for neutrophil to lymphocyte ratio as a predictor of diabetic retinopathy incidence in the Scottish population

BMC Medicine, 2023
Background Diabetic retinopathy (DR) is a major sight-threatening microvascular complication in individuals with diabetes. Systemic inflammation combined with oxidative stress is thought to capture most of the complexities involved in the pathology of ...
Aravind Lathika Rajendrakumar, Simona M. Hapca, Anand Thakarakkattil Narayanan Nair, Yu Huang, Mehul Kumar Chourasia, Ryan Shun-Yuen Kwan, Charvi Nangia, Moneeza K. Siddiqui, Prathiba Vijayaraghavan, Shona Z. Matthew, Graham P. Leese, Viswanathan Mohan, Ewan R. Pearson, Alexander S. F. Doney, Colin N. A. Palmer   +14 more
doaj   +1 more source

What is the association between childhood adversity and subsequent chronic pain in adulthood? A systematic review

BJA Open, 2023
Background: Adverse childhood experiences and chronic pain are complex problems affecting millions of people worldwide, and result in significant healthcare utilisation.
Karen P. Nicolson, Sarah E.E. Mills, Dhaneesha N.S. Senaratne, Lesley A. Colvin, Blair H. Smith   +4 more
doaj   +1 more source

Patient outcomes following AKI and AKD: a population-based cohort study

BMC Medicine, 2022
Background Acute kidney injury (AKI) is common and associated with adverse outcomes as well as important healthcare costs. However, evidence examining the epidemiology of acute kidney disease (AKD)—recently defined as AKI persisting between 7 and 90 days—
Huan Wang, Emilie Lambourg, Bruce Guthrie, Daniel R. Morales, Peter T. Donnan, Samira Bell   +5 more
doaj   +1 more source

Predictive performance of a competing risk cardiovascular prediction tool CRISK compared to QRISK3 in older people and those with comorbidity: population cohort study

BMC Medicine, 2022
Background Recommended cardiovascular disease (CVD) prediction tools do not account for competing mortality risk and over-predict incident CVD in older and multimorbid people. The aim of this study was to derive and validate a competing risk model (CRISK)
Shona J. Livingstone, Bruce Guthrie, Peter T. Donnan, Alexander Thompson, Daniel R. Morales   +4 more
doaj   +1 more source

Fine-mapping and identification of candidate causal genes for tail length in the Merinolandschaf breed

Communications Biology, 2022
Using SNP-association analysis and genetic mapping, a SNP and an insertion in and close to HOXB13 associated with short tail length is identified in Merino sheep, which may be a target for safely selecting shorter tails and improving sheep welfare.
Dominik Karl Lagler, Elisabeth Hannemann, Kim Eck, Jürgen Klawatsch, Doris Seichter, Ingolf Russ, Christian Mendel, Gesine Lühken, Stefan Krebs, Helmut Blum, Maulik Upadhyay, Ivica Medugorac   +11 more
doaj   +1 more source

Narrative review – Barriers and facilitators to promotion of physical activity in primary care

Lifestyle Medicine, 2023
The objective to provide an overview of the literature on the barriers and facilitators to physical activity (PA) promotion in primary care, as experienced by practitioners and patients.
Callum Leese, Kirstin Abraham, Blair H Smith   +2 more
doaj   +1 more source

Early experience with an opt-in research register - Scottish Health Research Register (SHARE): a multi-method evaluation of participant recruitment performance

BMC Medical Research Methodology, 2021
Background Recruiting participants to a clinical study is a resource-intensive process with a high failure rate. The Scottish Health Research Register (SHARE) provides recruitment support service which helps researchers recruit participants by searching ...
Wen Shi, Shobna Vasishta, Louise Dow, Daniella Cavellini, Colin Palmer, Brian McKinstry, Frank Sullivan   +6 more
doaj   +1 more source

Disentangling Ethiopian Honey Bee (Apis mellifera) Populations Based on Standard Morphometric and Genetic Analyses

Insects, 2021
The diversity and local differentiation of honey bees are subjects of broad general interest. In particular, the classification of Ethiopian honey bees has been a subject of debate for decades. Here, we conducted an integrated analysis based on classical
Teweldemedhn Gebretinsae Hailu, Paul D'Alvise, Martin Hasselmann   +2 more
doaj   +1 more source

The impact of phenotype, ethnicity and genotype on progression of type 2 diabetes mellitus

Endocrinology, Diabetes & Metabolism, 2020
Aim To conduct a comprehensive review of studies of glycaemic deterioration in type 2 diabetes and identify the major factors influencing progression. Methods We conducted a systematic literature search with terms linked to type 2 diabetes progression ...
Anand Thakarakkattil Narayanan Nair, Louise A. Donnelly, Adem Y. Dawed, Sushrima Gan, Ranjit M. Anjana, Mohan Viswanathan, Colin N. A. Palmer, Ewan R. Pearson   +7 more
doaj   +1 more source