Results 31 to 40 of about 661,661 (299)

Remapping of the belted phenotype in cattle on BTA3 identifies a multiplication event as the candidate causal mutation

open access: yesGenetics Selection Evolution, 2018
Background It has been known for almost a century that the belted phenotype in cattle follows a pattern of dominant inheritance. In 2009, the approximate position of the belt locus in Brown Swiss cattle was mapped to a 922-kb interval on bovine ...
Sophie Rothammer   +7 more
doaj   +1 more source

Inference of Bacterial Pathogen Instantaneous Population Growth Dynamics

open access: yesMolecular Plant-Microbe Interactions, 2020
Although bacterial host colonization is a dynamic process that requires population growth, studies often focus on comparing bacterial populations at a given time point. However, this may not reflect the dynamics of the colonization process.
Anne Sicard   +6 more
doaj   +1 more source

Population genomics in neglected malaria parasites

open access: yesFrontiers in Microbiology, 2022
Malaria elimination includes neglected human malaria parasites Plasmodium vivax, Plasmodium ovale spp., and Plasmodium malariae. Biological features such as association with low-density infection and the formation of hypnozoites responsible for relapse ...
Awtum M. Brashear, Liwang Cui
doaj   +1 more source

Population Genomics of Paramecium Species [PDF]

open access: yesMolecular Biology and Evolution, 2017
Population-genomic analyses are essential to understanding factors shaping genomic variation and lineage-specific sequence constraints. The dearth of such analyses for unicellular eukaryotes prompted us to assess genomic variation in Paramecium, one of the most well-studied ciliate genera.
Parul, Johri   +5 more
openaire   +2 more sources

Population genomics of marine zooplankton [PDF]

open access: yes, 2017
Author Posting. © The Author(s), 2017. This is the author's version of the work. It is posted here for personal use, not for redistribution. The definitive version was published in Bucklin, Ann et al.
A Biscontin   +242 more
core   +1 more source

Association of Gut Microbiota-Derived Short-Chain Fatty Acids With Persistent Elevated Serum Transaminase Levels in Normal Weight and Obesity: A Pilot Study

open access: yesJournal of Nutrition and Metabolism
Although obesity is the most common risk factor for hepatic steatosis, this disease may occur in normal-weight individuals. While gut microbial metabolites such as short-chain fatty acids (SCFAs) have been associated with obesity and metabolic disease ...
David Alberto Díaz de Sandy-Galán   +12 more
doaj   +1 more source

Ultra-accurate microbial amplicon sequencing with synthetic long reads

open access: yesMicrobiome, 2021
Background Out of the many pathogenic bacterial species that are known, only a fraction are readily identifiable directly from a complex microbial community using standard next generation DNA sequencing.
Benjamin J. Callahan   +4 more
doaj   +1 more source

The dynamics of alternative pathways to compensatory substitution [PDF]

open access: yes, 2013
The role of epistatic interactions among loci is a central question in evolutionary biology and is increasingly relevant in the genomic age. While the population genetics of compensatory substitution have received considerable attention, most studies ...
Nasrallah, Chris A.
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Clinical risk factors for unscheduled health care attendance for chronic pain management, and associated treatment costs

open access: yesPAIN Reports
. Introduction:. Effective community-based chronic noncancer pain (CNCP) management could improve treatment outcomes and reduce the burden placed on unscheduled care (USC) services. Objectives:.
Cassie Higgins   +2 more
doaj   +1 more source

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