Results 11 to 20 of about 4,860 (216)
A Population Genomics Lexicon [PDF]
AbstractPopulation genomics is a growing field stemming from soon a 100 years of developments in population genetics. Here, we summarize the main concepts and terminology underlying both theoretical and empirical statistical population genomics studies.
Barroso, G., Moutinho, A., Dutheil, J.
openaire +3 more sources
Population Genomics in the Great Apes [PDF]
AbstractThe great apes play an important role as model organisms. They are our closest living relatives, allowing us to identify the genetic basis of phenotypic traits that we think of as characteristically human. However, the most significant asset of great apes as model organisms is that they share with humans most of their genetic makeup. This means
Castellano, David +1 more
openaire +3 more sources
Population genomics of parallel adaptation [PDF]
Parallel evolution is one of the striking patterns in nature. The presence of repeated evolution of the same phenotypes, suites of traits, and adaptations suggests a strong role for natural selection in shaping biological diversity. The reasoning is straightforward: each instance of repeated evolution makes it less likely that these features evolved ...
Meng Yuan, John R. Stinchcombe
openaire +2 more sources
Ancestral Population Genomics [PDF]
The full genomes of several closely related species are now available, opening an emerging field of investigation borrowing both from population genetics and phylogenetics. Providing we can properly model sequence evolution within populations undergoing speciation events, this resource enables us to estimate key population genetics parameters, such as ...
Dutheil, J., Hobolth, A.
openaire +6 more sources
The diagnostic odyssey: insights from parents of children living with an undiagnosed condition
Background People living with rare disease often have protracted journeys towards diagnosis. In the last decade, programs have arisen around the world that are dedicated to ending this ‘diagnostic odyssey’, including the Undiagnosed Diseases Program ...
Alicia Bauskis +3 more
doaj +1 more source
The Application of Population Genomics in Crop Research
Population genomics is a rapidly developing discipline at the crossroads of population genetics and genomics [...]
Fan-Jing Yang, Wei Ma, Chu-Yu Ye
doaj +1 more source
The population genomics of plant adaptation [PDF]
SummaryThere has been an enormous increase in the amount of data on DNA sequence polymorphism available for many organisms in the last decade. New sequencing technologies provide great potential for investigating natural selection in plants using population genomic approaches.
Siol, Mathieu +2 more
openaire +3 more sources
Population Genomics of Human Adaptation [PDF]
Recent advances in genotyping technologies have facilitated genome-wide scans for natural selection. Detecting targets of natural selection sheds light on human evolution and it can help identify genetic variants that influence normal human phenotypic variation as well as disease susceptibility.
Joseph, Lachance, Sarah A, Tishkoff
openaire +2 more sources
Population Genomics of Paramecium Species [PDF]
Population-genomic analyses are essential to understanding factors shaping genomic variation and lineage-specific sequence constraints. The dearth of such analyses for unicellular eukaryotes prompted us to assess genomic variation in Paramecium, one of the most well-studied ciliate genera.
Parul, Johri +5 more
openaire +2 more sources
Population Genomics for Insect Conservation
Insects constitute vital components of ecosystems. There is alarming evidence for global declines in insect species diversity, abundance, and biomass caused by anthropogenic drivers such as habitat degradation or loss, agricultural practices, climate change, and environmental pollution.
Webster, Matthew Thomas +3 more
openaire +3 more sources

