Results 51 to 60 of about 50,070 (293)

Measuring and using admixture to study the genetics of complex diseases

Human Genomics, 2003
Admixture is an important evolutionary force that can and should be used in efforts to apply genomic data and technology to the study of complex disease genetics.
Halder Indrani, Shriver Mark D
doaj   +1 more source

Time since admixture.

, 2021
Estimated generations since admixture under a three-way admixture model: a founding mexicana population receives a pulse of parviglumis admixture and then a second pulse of maize admixture (possibly resulting in majority maize ancestry).
Anne Lorant (3930761), Graham Coop (86820), Jeffrey Ross-Ibarra (49029), M. Taylor Perkins (11547581), Erin Calfee (9537019), Daniel Gates (9728169)   +5 more
core   +1 more source

Habitat Predicts Levels of Genetic Admixture in Saccharomyces cerevisiae

G3: Genes, Genomes, Genetics, 2017
Genetic admixture can provide material for populations to adapt to local environments, and this process has played a crucial role in the domestication of plants and animals.
Viranga Tilakaratna, Douda Bensasson
doaj   +1 more source

Admixture, Population Structure, and F-Statistics [PDF]

Genetics, 2015
Abstract Many questions about human genetic history can be addressed by examining the patterns of shared genetic variation between sets of populations. A useful methodological framework for this purpose is F-statistics that measure shared genetic drift between sets of two, three, and four populations and can be used to test simple and ...
openaire   +3 more sources

Admixture in the Hispanics of the San Luis Valley, Colorado, and its implications for complex trait gene mapping [PDF]

, 2004
Hispanic populations are a valuable resource that can and should facilitate the identification of complex trait genes by means of admixture mapping (AM).
Bonilla, C, Ferrell, Robert E., Ferrell, RE, McKeigue, PM, Shriver, MD, Parra, EJ, Marshall, JA, Dios, S., Hamman, RF, Parra, E. J., McKeigue, P. M., Bonilla, C., Hoggart, C. L., Hoggart, CL, Dios, S, Shriver, M. D., Hamman, R. F., Marshall, J. A., Pfaff, Carrie Lynn, Pfaff, CL   +19 more
core   +1 more source

A panel of ancestry informative markers for the complex five-way admixed South African coloured population. [PDF]

PLoS ONE, 2013
Admixture is a well known confounder in genetic association studies. If genome-wide data is not available, as would be the case for candidate gene studies, ancestry informative markers (AIMs) are required in order to adjust for admixture. The predominant
Michelle Daya, Lize van der Merwe, Ushma Galal, Marlo Möller, Muneeb Salie, Emile R Chimusa, Joshua M Galanter, Paul D van Helden, Brenna M Henn, Chris R Gignoux, Eileen Hoal   +10 more
doaj   +1 more source

A Spatial Framework for Understanding Population Structure and Admixture [PDF]

PLOS Genetics, 2015
Geographic patterns of genetic variation within modern populations, produced by complex histories of migration, can be difficult to infer and visually summarize. A general consequence of geographically limited dispersal is that samples from nearby locations tend to be more closely related than samples from distant locations, and so genetic covariance ...
Bradburd, Gideon, Ralph, Peter L., Coop, Graham   +2 more
openaire   +5 more sources

Additional file 1 of AdmixSim 2: a forward-time simulator for modeling complex population admixture

, 2021
Additional file 1: Figure S1. Admixture models of population (A) African America (B) Mexican and (C) Uyghur. The numbers on the arrows represent the corresponding admixture proportions.
Kai Yuan (289810), Shuhua Xu (10278590), Xumin Ni (9113262), Yuwen Pan (7532864), Rui Zhang (13940), Chang Liu (35901)   +5 more
core   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

Inferring the population structure and admixture history of three Hmong-Mien-speaking Miao tribes from southwest China based on genome-wide SNP genotyping

Annals of Human Biology, 2021
Background Hmong-Mien speaking Miao, also called Hmong, is the sixth largest ethnic group in mainland China. However, the fine-scale genetic profiles and population history of Miao populations in southwest China, especially in Guizhou province, remain ...
Ting Luo, Rui Wang, Chuan-Chao Wang
doaj   +1 more source