Results 91 to 100 of about 704,078 (308)

Is telomere length a biomarker for aging: cross-sectional evidence from the west of Scotland? [PDF]

, 2012
Background <p> The search for biomarkers of aging (BoAs) has been largely unsuccessful to-date and there is widespread skepticism about the prospects of finding any that satisfy the criteria developed by the American Federation of Aging Research ...
Batty, G.D., Robertson, T., Shiels, PG, Shiels Paul G., Benzeval, Michaela, Michaela Benzeval, McGlynn, Liane, G David Batty, Ian J Deary, McIntyre, A., McIntyre, A, Michael J Green, Benzeval, M, Tony Robertson, Der, G, Alan McIntyre, Paul G Shiels, McIntyre Alan, Robertson, Tony, Shiels, Paul G, Green, Michael J, Green, M.J., McGlynn Liane, McIntyre, Alan, Deary, Ian J, Der, Geoff, Robertson, T, Geoff Der, Green, MJ, McGlynn, L., McGlynn, L, Green Michael J., Deary, Ian, Deary Ian J., Der, G., Liane McGlynn, Batty G. David, McGlynn, Liane M, Robertson Tony, Batty, GD, Benzeval, M., Shiels, P.G., Batty, G David, Benzeval Michaela, Deary, IJ, Deary, I.J., Der Geoff   +46 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Population Aging and Economic Growth: the effect of health expenditure [PDF]

Rising longevity has led to population aging in developed countries, causing increasing concerns about its economic impact. Specially, the trend of population aging increases health expenditure in developed countries, and 70% to 80% of health expenditure
Atsue Mizushima
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Social Security Reform in an Economy with Population Aging [PDF]

This paper analyzes the macroeconomic and welfare effects of population aging and Social Security reform. First, a stochastic overlapping-generations model with heterogeneous agents is carefully extended to an aging society.
Shinichi Nishiyama
core  

Impact papers on aging in 2009 [PDF]

, 2010
The editorial board of Aging reviews research papers published in 2009,which they believe have or will have a significant impact on aging research.Among many others, the topics include genes that accelerate aging or incontrast promote longevity in model ...
Sassone-Corsi, Paolo, Skulachev, Vladimir P., Tilly, Jonathan L., Hall, Michael N., Nussenzweig, Andre, Brunet, Anne, Blagosklonny, Mikhail V., Karlseder, Jan, Osiewacz, Heinz D., Jr, Robert M. Brosh, Blasco, Maria A., Gudkov, Andrei V., Rando, Thomas A., Serrano, Manuel, Peeper, Daniel S., Gorospe, Myriam, Donehower, Lawrence A, Tilly, Jonathan Lee, Brosh, Robert M, Jr, Robert M Brosh, Helfand, Stephen L, Brosh, Robert M., Finch, Caleb E., Osiewacz, Heinz D, Tower, John, Helfand, Stephen L., Sinclair, David A, Rudolph, K Lenhard, Campisi, Judy, Bohr, Vilhelm A, Skulachev, Vladimir P, Bohr, Vilhelm A., Gudkov, Andrei V, DePinho, Ronald A., Verdin, Eric, Bartke, Andrzej, Depinho, Ronald A, Kroemer, Guido, Rudolph, K. Lenhard, Peeper, Daniel S, Vijg, Jan, Rando, Thomas A, Tilly, Jonathan L, Bonner, William M., Kenyon, Cynthia, Finkel, Toren, Sinclair, David A., Hekimi, Siegfried, Hall, Michael N, Bonner, William M, Longo, Valter, Sinclair, David, Sharpless, Norman E, Sharpless, Norman E., Blagosklonny, Mikhail V, Finch, Caleb E, Donehower, Lawrence A., Blasco, Maria A   +57 more
core   +1 more source

Labor market effects of population aging [PDF]

This paper analyzes effects of population aging on the labor market and determines their broad implications for public policy. It takes Germany as an example, but it equally applies to the other large economies in Continental Europe.
Börsch-Supan, Axel
core   +4 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Ageing Population Risks [PDF]

, 2018
An ageing population is a major challenge for every country in the world arising from the declining fertility rate and increasing life expectancy. A longevity risk (the adverse outcome of people living longer than expected) exacerbated by declining equity returns coupled with the record low interest rate environments has significant implications for ...
openaire   +4 more sources

Population Aging and Its Economic Costs: A Survey of the Issues and Evidence [PDF]

The aging of the population is expected to result in substantial increases in the costs of maintaining health care and pension programs, and that is a source of widespread concern.
Byron G. Spencer, Frank T. Denton
core