Results 101 to 110 of about 6,228,730 (309)

The interplay of air pollution with plasma neurodegenerative markers and metabolome for dementia, Parkinson’s disease and all-cause mortality risks and transitions: The UK Biobank study

open access: yesEcotoxicology and Environmental Safety
We investigated the joint associations of circulating neurodegeneration markers—neurofilament light (NfL) and glial fibrillary acidic protein (GFAP)—ambient air pollution, and plasma metabolomic profiles with transitions from a healthy state to dementia,
May A. Beydoun   +11 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

[Coalition for Aging LGBT Pamphlet]

open access: yes
Pamphlet from the Coalition for Aging LGBT Records (The Dallas Way)
Coalition for Aging LGBT
core   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

open access: yes
Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi   +13 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Economic Security in an Aging Canadian Population [PDF]

open access: yes
This paper has been written to bring up to date materials in a monograph that was a part of the Butterworths series of monographs in social gerontology, in particular, the 1991 monograph entitled: Economic Security in an Aging Population (Brown, 1991 ...
Robert L. Brown
core   +2 more sources

Other title: [Kansas Department on Aging Overview]

open access: yes, 2009
application/pdf; "February 17, 2009."; Presentation before the Kansas Legislature, House Social Services Subcommittee on the Kansas Department on Aging, by Secretary Kathy Greenlee, Kansas Department on Aging.Presentation discussing the Governor's budget
Greenlee, Kathy.
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Geographic Dimensions of Aging in Canada 1991-2001 [PDF]

open access: yes
Although population aging at the national level has received much attention, its geographical dimensions have not. Here we explore the demographic processes which underlie population aging at the provincial and metropolitan scale for the periods 1991 ...
Michael A. Pacey, Eric G. Moore
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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