Results 91 to 100 of about 3,143,816 (338)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Türkiye'de Elektrik Tüketimi ve Ekonomik Büyüme Arasındaki İlişkinin Bölgesel Analizi

open access: yesEkonomi, Politika & Finans Araştırmaları Dergisi
Elektrik tüketimi ülkelerin gelişmişlik düzeyini ölçmede önemli bir gösterge olarak kabul edilmektedir. Ekonomik büyüme, kentleşme, beşerî sermaye gibi pek çok unsur elektrik tüketimi ile ilişkilidir.
Neslihan Ursavaş, Şükrü Apaydın
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Regional Determinants of Energy Efficiency: Residential Energy Demand in Japan

open access: yesEnergies, 2018
Controlling the rapid growth of residential energy demand and enhancing energy efficiency are key policy issues in Japan. Thus, this study aims to estimate a residential energy demand function by conducting a stochastic frontier analysis and analyze the ...
Akihiro Otsuka
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

An investigation of soil Chilopoda from Semeskandeh forest (Sari, Mazandaran, Iran) [PDF]

open access: yesتاکسونومی و بیوسیستماتیک, 2015
Present study was conducted to investigate soil Chilopoda and the density and diversity of them in different soil layers in Semeskandeh forest as an example of Hyrcanian forests during one year (2012 to 2013).
Mahmood Mehrafrooz Mayvan   +1 more
doaj  

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