Results 101 to 110 of about 1,450,630 (312)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Regional Determinants of Energy Efficiency: Residential Energy Demand in Japan

open access: yesEnergies, 2018
Controlling the rapid growth of residential energy demand and enhancing energy efficiency are key policy issues in Japan. Thus, this study aims to estimate a residential energy demand function by conducting a stochastic frontier analysis and analyze the ...
Akihiro Otsuka
doaj   +1 more source

Urban growth and population densities [PDF]

open access: yesDemography, 1973
Abstract Differences in the distribution of population within and across metropolitan areas are seen as a product of the development of the metropolis during different transportation epochs. Age cohorts of census tracts in Cleveland, Ohio, may be split into three groups of development patterns based on the time of their early development:
openaire   +2 more sources

Do population density, economic growth, energy use and exports adversely affect environmental quality in Asian populous countries?

open access: yes, 2017
This study aims to investigate the relationship between carbon dioxide (CO2) emissions, energy use, economic growth, exports and population density for a panel of 11 Asian populous countries over the period of 1960–2014. The panel cointegration tests and
Rahman, Mohammad Mafizur   +1 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

An investigation of soil Chilopoda from Semeskandeh forest (Sari, Mazandaran, Iran) [PDF]

open access: yesتاکسونومی و بیوسیستماتیک, 2015
Present study was conducted to investigate soil Chilopoda and the density and diversity of them in different soil layers in Semeskandeh forest as an example of Hyrcanian forests during one year (2012 to 2013).
Mahmood Mehrafrooz Mayvan   +1 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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