Results 101 to 110 of about 3,149,527 (289)
Ecology and Society, 2002 This paper explores the effects of spatial resolution on the performance and applicability of habitat models in wildlife management and conservation. A Habitat Suitability Index (HSI) model for the Capercaillie (Tetrao urogallus) in the Bavarian Alps ...
Ilse Storch
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Evolutionary Stable Strategies Depending on Population Density [PDF]
, 1990 The concept of evolutionary stable strategies is extended to include density dependence. Dynamical stability is shown to follow for two-strategy games and for symmetric payoff matrices.
Cressman, Ross
core +1 more source
Urban growth and population densities [PDF]
Demography, 1973 Abstract Differences in the distribution of population within and across metropolitan areas are seen as a product of the development of the metropolis during different transportation epochs. Age cohorts of census tracts in Cleveland, Ohio, may be split into three groups of development patterns based on the time of their early development:
openaire +2 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Classical models of urban population density. The case of Barcelona Metropolitan Area [PDF]
In this paper, we study the classical functional forms density-distance and its relation with the suburbanization for the Barcelona Metropolitan Area.
Joan Carles Martori +1 more
core
Using poststratification to improve abundance estimates from multispecies surveys: a study of juvenile flatfishes [PDF]
, 2005 Population assessments seldom incorporate habitat information or use previously observed distributions of fish density. Because habitat affects the spatial distribution of fish density and overall abundance, the use of habitat information and previous ...
Dressel, Sherri C.
core
Quality-Adjusted Population Density [PDF]
SSRN Electronic Journal, 2020 J. Vernon Henderson +2 more
openaire +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source