Results 91 to 100 of about 8,466,171 (303)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

SPATIAL ANALYSIS OF EMPLOYMENT AND POPULATION DENSITY: THE CASE OF THE AGGLOMERATION OF DIJON, 1999 [PDF]

open access: yes
The aim of this paper is to analyze the intra-urban spatial distributions of population and employment in the agglomeration of Dijon (regional capital of Burgundy, France).
Julie Le Gallo   +2 more
core  

Regional Determinants of Energy Efficiency: Residential Energy Demand in Japan

open access: yesEnergies, 2018
Controlling the rapid growth of residential energy demand and enhancing energy efficiency are key policy issues in Japan. Thus, this study aims to estimate a residential energy demand function by conducting a stochastic frontier analysis and analyze the ...
Akihiro Otsuka
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Cubic spline population density functions and subcentre delimitation. The case of Barcelona [PDF]

open access: yes
The presence of subcentres cannot be captured by an exponential function. Cubic spline functions seem more appropriate to depict the polycentricity pattern of modern urban systems.
Anna Galindo   +2 more
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

New Zealand regions, 1986-2001: Population structures [PDF]

open access: yes, 2005
The age structure of a region’s population affects many areas of social and economic development across all sectors, including employment, housing, welfare, health and education.
Lindop, J.   +3 more
core  

Video: Population Council 70th Anniversary

open access: yes, 2022
For 70 years, the Population Council has transformed global thinking on critical health and development issues through our social science, public health, and biomedical research.
Population Council
core   +1 more source

An investigation of soil Chilopoda from Semeskandeh forest (Sari, Mazandaran, Iran) [PDF]

open access: yesتاکسونومی و بیوسیستماتیک, 2015
Present study was conducted to investigate soil Chilopoda and the density and diversity of them in different soil layers in Semeskandeh forest as an example of Hyrcanian forests during one year (2012 to 2013).
Mahmood Mehrafrooz Mayvan   +1 more
doaj  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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