Results 111 to 120 of about 753,387 (250)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Métodos estatísticos e estrutura espacial de populações: uma análise comparativa = Statistic methods and population spatial structure: a comparative analyses

open access: yesActa Scientiarum: Technology, 2006
O presente estudo teve por objetivo comparar os resultados de distribuição espacial obtidos entre os métodos clássicos e os métodos que estimam a variância entre parcelas. Foram analisadas duas espécies, Vernonia aurea e Duguetia furfuracea.
Matheus de Souza Lima-Ribeiro   +1 more
doaj  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Abiotic factors and population dynamic of Aedes aegypti and Aedes albopictus in an endemic area of dengue in Brazil. [PDF]

open access: yesRev Inst Med Trop Sao Paulo, 2019
Custódio JMO   +7 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Inferring forest fate from demographic data: from vital rates to population dynamic models. [PDF]

open access: yesProc Biol Sci, 2018
Needham J   +4 more
europepmc   +1 more source

POPULATION DYNAMICS [PDF]

open access: yesAmerican Journal of Public Health and the Nations Health, 1967
openaire   +1 more source

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