Results 91 to 100 of about 2,891,099 (365)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Embedding Population Dynamics Models in Inference

, 2007
Increasing pressures on the environment are generating an ever-increasing need to manage animal and plant populations sustainably, and to protect and rebuild endangered populations.
Buckland, Stephen T., Fernández, Carmen, Harwood, John, Newman, Ken B., Thomas, Len   +4 more
core   +3 more sources

Migration Dynamics for the Ideal Free Distribution [PDF]

, 2006
This article verifies that the ideal free distribution (IFD) is evolutionarily stable, provided the payoff in each patch decreases with an increasing number of individuals.
Cressman, Ross, Křivan, Vlastimil
core   +2 more sources

Population Dynamics of Bacterial Persistence

PLoS ONE, 2013
Persistence is a prime example of phenotypic heterogeneity, where a microbial population splits into two distinct subpopulations with different growth and survival properties as a result of reversible phenotype switching. Specifically, persister cells grow more slowly than normal cells under unstressed growth conditions, but survive longer under stress
Patra, P., Klumpp, S.
openaire   +6 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Protective sexual behaviours among young adults in Nigeria: influence of family support and living with both parents

BMC Public Health, 2019
Background Many studies have focused on risky sexual behaviour among adolescents and young adults; however, literature on protective sexual practices among this age cohort is still evolving.
Anthony Idowu Ajayi, Sylvester Reuben Okeke   +1 more
doaj   +1 more source

Population genetic consequences of the Allee effect and the role of offspring-number variation [PDF]

arXiv, 2013
A strong demographic Allee effect in which the expected population growth rate is negative below a certain critical population size can cause high extinction probabilities in small introduced populations. However, many species are repeatedly introduced to the same location and eventually one population may overcome the Allee effect by chance.
arxiv  

Asymptotic properties of stochastic population dynamics [PDF]

, 2008
In this paper we stochastically perturb the classical Lotka{Volterra model x_ (t) = diag(x1(t); ; xn(t))[b + Ax(t)] into the stochastic dierential equation dx(t) = diag(x1(t); ; xn(t))[(b + Ax(t))dt + dw(t)]: The main aim is to study the asymptotic ...
Deng, Feiqi, EPSRC (U.K.) (Funder), Jinan University of China (Funder), Key Programs of Science and Technology of Guangzhou (Funder), Mao, Xuerong, National Natural Science Foundation of China (Funder), Pang, Sulin   +6 more
core  

Stochastic population dynamics in turbulent fields

, 2007
The behavior of interacting populations typically displays irregular temporal and spatial patterns that are difficult to reconcile with an underlying deterministic dynamics.
Rubi, J. M., Vainstein, M. H., Vilar, J. M. G.   +2 more
core   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source