Results 91 to 100 of about 2,848,057 (332)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Ageing populations: new challenges in longevity

BMC Public Health
Background High-income countries experienced unprecedented gains in life expectancy throughout the twentieth century. However, recent evidence suggests that these gains have slowed, especially at older ages.
Julia Callaway, Cosmo Strozza, Kaare Christensen, Gabriele Doblhammer, Roland Rau, Jes Søgaard   +5 more
doaj   +1 more source

Challenges in the case-based surveillance of infectious diseases

Royal Society Open Science
To effectively inform infectious disease control strategies, accurate knowledge of the pathogen’s transmission dynamics is required. Since the timings of infections are rarely known, estimates of the infection incidence, which is crucial for ...
Oliver Eales, James M. McCaw, Freya M. Shearer   +2 more
doaj   +1 more source

Complexity and hierarchical game of life

, 2003
Hierarchical structure is an essential part of complexity, important notion relevant for a wide range of applications ranging from biological population dynamics through robotics to social sciences.
Berlekamp E. R., BORIS ZALTZMAN, EUGENE TZVETKOV, Gardner M., ISAAK RUBINSTEIN, IVAN GÖTZ   +5 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Population dynamics of Windermere perch [PDF]

, 1982
This paper looks briefly at some of the more recent analyses and interpretations of the changes that have occurred in the population dynamics of Windermere perch and at the present level of understanding.
Craig, J.F.
core  

A scale-invariant model of marine population dynamics

, 2010
A striking feature of the marine ecosystem is the regularity in its size spectrum: the abundance of organisms as a function of their weight approximately follows a power law over almost ten orders of magnitude.
Capitan, Jose A., Delius, Gustav W.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Morphology of Peripheral Blood Cells from Various Species of Turkish Herpetofauna

Acta Herpetologica, 2010
In this study, measurements of morphological and size parameters of peripheral blood cells (erythrocyte, leucocyte, thrombocyte) on blood smear preparation devices stained with Wright’s stain were given for 87 species from Turkish herpetofauna (19 ...
Hüseyin ARIKAN, Kerim CICEK
doaj   +1 more source