Results 81 to 90 of about 2,848,057 (332)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Convergence of generalized urn models to non-equilibrium attractors

open access: yes, 2014
Generalized Polya urn models have been used to model the establishment dynamics of a small founding population consisting of k different genotypes or strategies.
Faure, Mathieu, Schreiber, Sebastian
core   +3 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Spatiotemporal profiling reveals the impact of caloric restriction in the aging mammalian brain

open access: yesCell Reports
Summary: Caloric restriction (CR) is a well-studied intervention that extends lifespan and slows cognitive decline across species, yet the specific cell populations and molecular pathways involved remain elusive. In this study, we profiled >500,000 cells
Zehao Zhang   +6 more
doaj   +1 more source

Protective sexual behaviours among young adults in Nigeria: influence of family support and living with both parents

open access: yesBMC Public Health, 2019
Background Many studies have focused on risky sexual behaviour among adolescents and young adults; however, literature on protective sexual practices among this age cohort is still evolving.
Anthony Idowu Ajayi   +1 more
doaj   +1 more source

Visualizing population dynamics of alaska\u27s arctic communities [PDF]

open access: yes, 2009
Arctic demography has previously been reviewed on a large scale, across the circumpolar nations. We look instead at some recent population dynamics on sub-regional to community scales, focusing on Arctic Alaska.
Hamilton, Lawrence C., Mitiguy, Angela M
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

The balance of growth and risk in population dynamics

open access: yes, 2017
Essential to each other, growth and exploration are jointly observed in populations, be it alive such as animals and cells or inanimate such as goods and money. But their ability to move, crucial to cope with uncertainty and optimize returns, is tempered
Gueudré, Thomas, Martin, David
core   +1 more source

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