Results 81 to 90 of about 2,869,951 (334)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Youth smoking and anti-smoking policies in North Dakota: a system dynamics simulation study
Substance Abuse Treatment, Prevention, and Policy, 2019 Background The current study utilizes system dynamics to model the determinants of youth smoking and simulate effects of anti-smoking policies in the context of North Dakota, a state with one of the lowest cigarette tax rates in the USA.
Arielle S. Selya +3 more
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Odour-mediated sexual attraction in nabids (Heteroptera: Nabidae)
European Journal of Entomology, 2008 In many insects, mate finding is mediated by volatile sex pheromones, but evidence in nabids is still fragmentary. The role of odour-mediated sexual attraction in two nabid species, Nabis pseudoferus and N.
Steffen ROTH +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Convergence of generalized urn models to non-equilibrium attractors
, 2014 Generalized Polya urn models have been used to model the establishment dynamics of a small founding population consisting of k different genotypes or strategies.
Faure, Mathieu, Schreiber, Sebastian
core +3 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Mate limitation, recurrent epidemic outbreaks, and the coexistence of sexual and asexual plant parasites [PDF]
, 2014 To date, relatively few studies have focused on the effects of sex on population dynamics. Previous models found that sexual reproduction may either dampen population fluctuations or accentuate population fluctuations, depending on mating system notably.
Hamelin, Frédéric +3 more
core
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Spatiotemporal profiling reveals the impact of caloric restriction in the aging mammalian brain
Cell ReportsSummary: Caloric restriction (CR) is a well-studied intervention that extends lifespan and slows cognitive decline across species, yet the specific cell populations and molecular pathways involved remain elusive. In this study, we profiled >500,000 cells
Zehao Zhang +6 more
doaj +1 more source