Results 11 to 20 of about 7,398,608 (386)
Molecular Population Genetics [PDF]
Genetics, 2017 Molecular population genetics aims to explain genetic variation and molecular evolution from population genetics principles. The field was born 50 years ago with the first measures of genetic variation in allozyme loci, continued with the nucleotide ...
Sònia Casillas, A. Barbadilla
semanticscholar +3 more sources
Population genetics in microchannels
Proceedings of the National Academy of Sciences, 2022 Significance Many microbial populations proliferate in small channels. In such environments, reproducing cells organize in parallel lanes. Reproducing cells shift these lanes, potentially expelling other cells from the channel. In this paper, we combine theory and experiments to understand how these dynamics affects the diversity
Anzhelika Koldaeva +3 more
openaire +3 more sources
The population genetics of dN/dS. [PDF]
PLoS Genetics, 2008 Evolutionary pressures on proteins are often quantified by the ratio of substitution rates at non-synonymous and synonymous sites. The dN/dS ratio was originally developed for application to distantly diverged sequences, the differences among which ...
Sergey Kryazhimskiy, Joshua B Plotkin
doaj +1 more source
Pedigree Analysis: A Team-Based Learning Activity
MedEdPORTAL, 2017 Introduction Regardless of their specialty, physicians, particularly those practicing primary care in rural areas, typically encounter genetic conditions.
Jack Thatcher +3 more
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Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes
Nature Communications, 2020 Multi-nucleotide variants (MNV) are genetic variants in close proximity of each other on the same haplotype whose functional impact is difficult to predict if they reside in the same codon. Here, Wang et al. use the gnomAD dataset to assemble a catalogue
Qingbo Wang +11 more
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The wild tomato species Solanum chilense shows variation in pathogen resistance between geographically distinct populations [PDF]
PeerJ, 2017 Wild tomatoes are a valuable source of disease resistance germplasm for tomato (Solanum lycopersicum) breeders. Many species are known to possess a certain degree of resistance against certain pathogens; however, evolution of resistance traits is yet ...
Remco Stam +2 more
doaj +2 more sources
The nk model and population genetics [PDF]
, 2005 The nk model of fitness interactions is examined. This model has been used by previous authors to investigate the effects of fitness epistasis on substitution dynamics in molecular evolution, and to make broader claims about the importance of epistasis ...
Barton +54 more
core +2 more sources
Arlequin (version 3.0): An integrated software package for population genetics data analysis
Evolutionary bioinformatics online, 2005 Arlequin ver 3.0 is a software package integrating several basic and advanced methods for population genetics data analysis, like the computation of standard genetic diversity indices, the estimation of allele and haplotype frequencies, tests of ...
L. Excoffier +2 more
semanticscholar +1 more source
A Primer of Population Genetics and Genomics
, 2020 A Primer of Population Genetics and Genomics, 4th edition, has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics.
D. Hartl
semanticscholar +1 more source
The Pennsylvania grotto sculpin: population genetics [PDF]
Subterranean Biology, 2021 The Pennsylvania grotto sculpin is known from just two caves of the Nippenose Valley in central Pennsylvania, USA. They exhibit emergent troglobitic morphological traits and are the second northern-most cave adapted fish in the world.
Luis Espinasa +2 more
doaj +3 more sources