Results 11 to 20 of about 6,710,675 (378)

Molecular Population Genetics [PDF]

open access: yesGenetics, 2017
Molecular population genetics aims to explain genetic variation and molecular evolution from population genetics principles. The field was born 50 years ago with the first measures of genetic variation in allozyme loci, continued with the nucleotide ...
Sònia Casillas, A. Barbadilla
semanticscholar   +3 more sources

k-mer-based approaches to bridging pangenomics and population genetics [PDF]

open access: yesarXiv
Many commonly studied species now have more than one chromosome-scale genome assembly, revealing a large amount of genetic diversity previously missed by approaches that map short reads to a single reference. However, many species still lack multiple reference genomes and correctly aligning references to build pangenomes is challenging, limiting our ...
Roberts MD   +3 more
arxiv   +2 more sources

Population genetics in microchannels

open access: yesProceedings of the National Academy of Sciences, 2022
Significance Many microbial populations proliferate in small channels. In such environments, reproducing cells organize in parallel lanes. Reproducing cells shift these lanes, potentially expelling other cells from the channel. In this paper, we combine theory and experiments to understand how these dynamics affects the diversity
Anzhelika Koldaeva   +3 more
openaire   +3 more sources

Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows

open access: yesMolecular Ecology Resources, 2010
We present here a new version of the Arlequin program available under three different forms: a Windows graphical version (Winarl35), a console version of Arlequin (arlecore), and a specific console version to compute summary statistics (arlsumstat).
L. Excoffier, H. Lischer
semanticscholar   +1 more source

The population genetics of dN/dS. [PDF]

open access: yesPLoS Genetics, 2008
Evolutionary pressures on proteins are often quantified by the ratio of substitution rates at non-synonymous and synonymous sites. The dN/dS ratio was originally developed for application to distantly diverged sequences, the differences among which ...
Sergey Kryazhimskiy, Joshua B Plotkin
doaj   +1 more source

Pedigree Analysis: A Team-Based Learning Activity

open access: yesMedEdPORTAL, 2017
Introduction Regardless of their specialty, physicians, particularly those practicing primary care in rural areas, typically encounter genetic conditions.
Jack Thatcher   +3 more
doaj   +1 more source

The wild tomato species Solanum chilense shows variation in pathogen resistance between geographically distinct populations [PDF]

open access: yesPeerJ, 2017
Wild tomatoes are a valuable source of disease resistance germplasm for tomato (Solanum lycopersicum) breeders. Many species are known to possess a certain degree of resistance against certain pathogens; however, evolution of resistance traits is yet ...
Remco Stam   +2 more
doaj   +2 more sources

Population Genetics

open access: yesDefinitions, 2020
There are thousands of ebooks available to download legally – either because their copyright has expired, or because their authors have chosen to release them without charge.
Brian Charlesworth, Jeffrey D. Jensen
semanticscholar   +1 more source

Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

open access: yesNature Communications, 2020
Multi-nucleotide variants (MNV) are genetic variants in close proximity of each other on the same haplotype whose functional impact is difficult to predict if they reside in the same codon. Here, Wang et al. use the gnomAD dataset to assemble a catalogue
Qingbo Wang   +11 more
doaj   +1 more source

Active information requirements for fixation on the Wright-Fisher model of population genetics [PDF]

open access: yesBIO-Complexity 2020(4):1-6, 2021
In the context of population genetics, active information can be extended to measure the change of information of a given event (e.g., fixation of an allele) from a neutral model in which only genetic drift is taken into account to a non-neutral model that includes other sources of frequency variation (e.g., selection and mutation).
arxiv   +1 more source

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