Results 31 to 40 of about 6,377,716 (133)

Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

Nature Communications, 2020
Multi-nucleotide variants (MNV) are genetic variants in close proximity of each other on the same haplotype whose functional impact is difficult to predict if they reside in the same codon. Here, Wang et al. use the gnomAD dataset to assemble a catalogue
Qingbo Wang, Emma Pierce-Hoffman, Beryl B. Cummings, Jessica Alföldi, Laurent C. Francioli, Laura D. Gauthier, Andrew J. Hill, Anne H. O’Donnell-Luria, Genome Aggregation Database Production Team, Genome Aggregation Database Consortium, Konrad J. Karczewski, Daniel G. MacArthur   +11 more
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Mantel test in population genetics

Genetics and Molecular Biology, 2013
The comparison of genetic divergence or genetic distances, estimated by pairwise F ST and related statistics, with geographical distances by Mantel test is one of the most popular approaches to evaluate spatial processes driving population structure ...
José Alexandre F. Diniz-Filho, Thannya N. Soares, Jacqueline S. Lima, Ricardo Dobrovolski, Victor Lemes Landeiro, Mariana Pires de Campos Telles, Thiago F. Rangel, Luis Mauricio Bini   +7 more
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Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots

Nature Communications, 2022
The inherited basis of body fat distribution is not fully understood. Here, the authors use genetic data and MRI-derived measures of local adiposity to highlight fat depot-specific genetic architecture with implications for cardiometabolic health.
Saaket Agrawal, Minxian Wang, Marcus D. R. Klarqvist, Kirk Smith, Joseph Shin, Hesam Dashti, Nathaniel Diamant, Seung Hoan Choi, Sean J. Jurgens, Patrick T. Ellinor, Anthony Philippakis, Melina Claussnitzer, Kenney Ng, Miriam S. Udler, Puneet Batra, Amit V. Khera   +15 more
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Beyond Biodiversity: Can Environmental DNA (eDNA) Cut It as a Population Genetics Tool?

Genes, 2019
Population genetic data underpin many studies of behavioral, ecological, and evolutionary processes in wild populations and contribute to effective conservation management.
Clare M. Adams, M. Knapp, N. Gemmell, Gert‐Jan Jeunen, M. Bunce, M. Lamare, H. Taylor   +6 more
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A Primer of Population Genetics and Genomics

, 2020
A Primer of Population Genetics and Genomics, 4th edition, has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics.
D. Hartl
semanticscholar   +1 more source

Neutral genomic signatures of host-parasite coevolution

BMC Evolutionary Biology, 2019
Background Coevolution is a selective process of reciprocal adaptation in hosts and parasites or in mutualistic symbionts. Classic population genetics theory predicts the signatures of selection at the interacting loci of both species, but not the ...
Daniel živković, Sona John, Mélissa Verin, Wolfgang Stephan, Aurélien Tellier   +4 more
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Population genetics of forest trees.

Silva Fennica, 1982
The publication comprises proceedings of a conference held in Helsinki in 1981. Forest tree populations are investigated for population genetic structure, mating systems, mechanisms of genetic adaptation and ecological adaptation.
Tigerstedt, P.
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Transposon-induced epigenetic silencing in the X chromosome as a novel form of dmrt1 expression regulation during sex determination in the fighting fish

BMC Biology, 2022
Background Fishes are the one of the most diverse groups of animals with respect to their modes of sex determination, providing unique models for uncovering the evolutionary and molecular mechanisms underlying sex determination and reversal.
Le Wang, Fei Sun, Zi Yi Wan, Zituo Yang, Yi Xuan Tay, May Lee, Baoqing Ye, Yanfei Wen, Zining Meng, Bin Fan, Yuzer Alfiko, Yubang Shen, Francesc Piferrer, Axel Meyer, Manfred Schartl, Gen Hua Yue   +15 more
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Efficient pedigree recording for fast population genetics simulation

bioRxiv, 2018
In this paper we describe how to efficiently record the entire genetic history of a population in forwards-time, individual-based population genetics simulations with arbitrary breeding models, population structure and demography.
Jerome Kelleher, Kevin R. Thornton, Jaime Ashanderf, Peter L. Ralph   +3 more
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FinnGen provides genetic insights from a well-phenotyped isolated population

Nature, 2023
Genome-wide association studies of individuals from an isolated population (data from the Finnish biobank study FinnGen) and consequent meta-analyses facilitate the identification of previously unknown coding variant associations for both rare and common
M. Kurki, J. Karjalainen, P. Palta, Timo P. Sipilä, K. Kristiansson, K. Donner, M. Reeve, H. Laivuori, M. Aavikko, M. Kaunisto, A. Loukola, E. Lahtela, Hannele Mattsson, P. Laiho, Pietro della Briotta Parolo, Arto A Lehisto, M. Kanai, N. Mars, Joel T. Rämö, T. Kiiskinen, H. Heyne, K. Veerapen, S. Rüeger, S. Lemmelä, Wei Zhou, S. Ruotsalainen, K. Pärn, T. Hiekkalinna, Sami Koskelainen, T. Paajanen, Vincent Llorens, Javier Gracia-Tabuenca, H. Siirtola, Kadri Reis, A. Elnahas, B. Sun, Christopher N. Foley, K. Aalto-Setälä, Kaur Alasoo, Mikko Arvas, K. Auro, Shameek Biswas, Argyro Bizaki-Vallaskangas, O. Carpén, Chia-Yen Chen, O. A. Dada, Zhihao Ding, M. Ehm, K. Eklund, M. Färkkilä, H. Finucane, A. Ganna, A. Ghazal, R. Graham, Eric M. Green, A. Hakanen, Marco Hautalahti, Å. Hedman, M. Hiltunen, R. Hinttala, I. Hovatta, Xinli Hu, A. Huertas-Vazquez, L. Huilaja, J. Hunkapiller, H. Jacob, J. Jensen, H. Joensuu, Sally John, V. Julkunen, M. Jung, J. Junttila, K. Kaarniranta, M. Kähönen, Risto Kajanne, Lila Kallio, R. Kälviäinen, J. Kaprio, N. Kerimov, J. Kettunen, Elina Kilpeläinen, T. Kilpi, Katherine W. Klinger, V. Kosma, T. Kuopio, Venla Kurra, T. Laisk, J. Laukkanen, Nathan Lawless, Aoxing Liu, S. Longerich, R. Mägi, J. Mäkelä, Antti A. Mäkitie, A. Malarstig, A. Mannermaa, Joseph C. Maranville, A. Matakidou, T. Meretoja, S. Mozaffari, Mari E. K. Niemi, Mari E. K. Niemi, T. Niiranen, Christopher J O 'donnell, M. Obeidat, G. Okafo, H. Ollila, A. Palomäki, T. Palotie, J. Partanen, D. Paul, Margit K. Pelkonen, Rion K. Pendergrass, S. Petrovski, A. Pitkäranta, A. Platt, D. Pulford, E. Punkka, P. Pussinen, Neha S. Raghavan, F. Rahimov, D. Rajpal, N. Renaud, B. Riley-Gillis, R. Rodosthenous, Elmo C. Saarentaus, A. Salminen, Eveliina Salminen, V. Salomaa, J. Schleutker, R. Serpi, Huei-yi Shen, R. Siegel, K. Silander, S. Siltanen, S. Soini, H. Soininen, J. Sul, I. Tachmazidou, K. Tasanen, P. Tienari, S. Toppila-Salmi, T. Tukiainen, T. Tuomi, J. Turunen, J. Ulirsch, F. Vaura, P. Virolainen, J. Waring, D. Waterworth, Robert Yang, M. Nelis, A. Reigo, A. Metspalu, L. Milani, T. Esko, Caroline Fox, A. Havulinna, M. Perola, S. Ripatti, A. Jalanko, Tarja Laitinen, T. Mäkelä, R. Plenge, M. McCarthy, H. Runz, M. Daly, A. Palotie   +167 more
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