Results 41 to 50 of about 6,710,675 (378)
Background Quantitative traits are typically considered to be under additive genetic control. Although there are indications that non-additive factors have the potential to contribute to trait variation, experimental demonstration remains scarce.
Francois Besnier+11 more
doaj +1 more source
Genetic similarity versus genetic ancestry groups as sample descriptors in human genetics [PDF]
A common sample descriptor in human genomics studies is that of 'genetic ancestry group', with terms such as 'European genetic ancestry' or 'East Asian genetic ancestry' frequently used in publications to describe the genetics of groups of individuals based on the analysis of their genotypes.
arxiv
The opportunities and challenges of integrating population histories into genetic studies of diverse populations: a motivating example from Native Hawaiians [PDF]
There is an urgent and well-recognized need to extend genetic studies to diverse populations, but several obstacles continue to be prohibitive, including (but not limited to) the difficulty of recruiting individuals from diverse populations in large numbers and the lack of representation in available genomic references. These obstacles notwithstanding,
arxiv +1 more source
Efficient pedigree recording for fast population genetics simulation
In this paper we describe how to efficiently record the entire genetic history of a population in forwards-time, individual-based population genetics simulations with arbitrary breeding models, population structure and demography.
Jerome Kelleher+3 more
semanticscholar +1 more source
Human genetic admixture through the lens of population genomics [PDF]
Over the last fifty years, geneticists have made great strides in understanding how our species' evolutionary history gave rise to current patterns of human genetic diversity classically summarized by Lewontin in his 1972 paper, 'The Apportionment of Human Diversity'.
arxiv
Population Genetics with Fluctuating Population Sizes [PDF]
Standard neutral population genetics theory with a strictly fixed population size has important limitations. An alternative model that allows independently fluctuating population sizes and reproduces the standard neutral evolution is reviewed.
Thiparat Chotibut, D. Nelson
semanticscholar +1 more source
Dismantling a dogma: the inflated significance of neutral genetic diversity in conservation genetics [PDF]
The current rate of species extinction is rapidly approaching unprecedented highs and life on Earth presently faces a sixth mass extinction event driven by anthropogenic activity, climate change and ecological collapse. The field of conservation genetics aims at preserving species by using their levels of genetic diversity, usually measured as neutral ...
arxiv +1 more source
In the article by S. Casillas and A. Barbadilla (GENETICS 205: 1003–1035) entitled “Molecular Population Genetics,” on page 1010, the references provided in Table 1 were incomplete. For the measure/test vA, the reference to “Castellano et al.
Matthew W. Hahn
semanticscholar +1 more source
Inbreeding depression, the loss of offspring fitness due to consanguineous mating, is generally detrimental for individual performance and population viability.
A. J. Paijmans+6 more
doaj +1 more source
Neutral Theory, Microbial Practice: Challenges in Bacterial Population Genetics
I detail four major open problems in microbial population genetics with direct implications to the study of molecular evolution: the lack of neutral polymorphism, the modeling of promiscuous genetic exchanges, the genetics of ill‐defined populations, and
E. Rocha
semanticscholar +1 more source