Results 121 to 130 of about 8,031,804 (248)

Human Disease Variation in the Light of Population Genomics.

Cell, 2019
Identifying the causes of similarities and differences in genetic disease prevalence among humans is central to understanding disease etiology. While present-day humans are not strongly differentiated, vast amounts of genomic data now make it possible to
Ana Prohaska, Ana Prohaska, F. Racimo, A. Schork, A. Schork, A. Schork, M. Sikora, A. Stern, Melissa Ilardo, Melissa Ilardo, M. Allentoft, L. Folkersen, L. Folkersen, L. Folkersen, Alfonso Buil, Alfonso Buil, Alfonso Buil, J. V. Moreno-Mayar, T. Korneliussen, D. Geschwind, D. Geschwind, A. Ingason, A. Ingason, A. Ingason, T. Werge, Rasmus Nielsen, Rasmus Nielsen, E. Willerslev, E. Willerslev   +28 more
semanticscholar   +1 more source

‘Forging healthy communities’: a service evaluation of a 12-week community-based exercise, nutrition, behaviour change and peer-support programme

BMC Public Health
Background Physical inactivity is a leading cause of premature mortality and morbidity worldwide. Primary care settings provide an opportunity for effective lifestyle interventions, including physical activity (PA) promotion.
Callum Leese, Blair H. Smith, Rosina Cross, Emma J. Cockcroft, Cassie Higgins   +4 more
doaj   +1 more source

Genetic variation in the Middle East—an opportunity to advance the human genetics field

Genome Medicine, 2020
We highlight the current lack of representation of the Middle East from large genomic studies and emphasize the expected high impact of cataloging its variation.
Ahmad N. Abou Tayoun, Heidi L. Rehm
doaj   +1 more source

Population Genomics of GII.4 Noroviruses Reveal Complex Diversification and New Antigenic Sites Involved in the Emergence of Pandemic Strains

mBio, 2019
Noroviruses are an important cause of viral gastroenteritis around the world. An obstacle delaying the development of norovirus vaccines is inadequate understanding of the role of norovirus diversity in immunity.
K. Tohma, C. Lepore, Yamei Gao, L. A. Ford-Siltz, G. I. Parra   +4 more
semanticscholar   +1 more source

Population genomics of the Viking world

Nature, 2019
The maritime expansion of Scandinavian populations during the Viking Age (about ad 750–1050) was a far-flung transformation in world history1,2. Here we sequenced the genomes of 442 humans from archaeological sites across Europe and Greenland (to a ...
Ashot Margaryan, Ashot Margaryan, Daniel J. Lawson, M. Sikora, F. Racimo, Simon Rasmussen, Ida Moltke, Lara M. Cassidy, Emil Jørsboe, A. Ingason, A. Ingason, M. W. Pedersen, T. Korneliussen, T. Korneliussen, H. Wilhelmson, M. Bus, P. B. Damgaard, Rui Martiniano, Gabriel Renaud, Gabriel Renaud, Claude Bhérer, J. V. Moreno-Mayar, A. Fotakis, M. Allen, Raili Allmäe, Martyna Molak, E. Cappellini, G. Scorrano, Hugh McColl, A. Buzhilova, Allison Fox, A. Albrechtsen, Berit Schütz, B. Skar, C. Arcini, Ceri Falys, Charlotte Hedenstierna Jonson, Dariusz Blaszczyk, D. Pezhemsky, G. Turner‐Walker, H. Gestsdóttir, I. Lundstrøm, Ingrid Gustin, I. Mainland, I. Potekhina, I. M. Muntoni, J. Cheng, Jesper T. Stenderup, Jilong Ma, Julie Gibson, Jüri Peets, J. Gustafsson, K. H. Iversen, K. H. Iversen, Linzi Simpson, L. Strand, L. Loe, Maeve Sikora, M. Florek, Maria Vretemark, M. Redknap., Monika Bajka, T. Pushkina, Morten Søvsø, N. Grigoreva, T. Christensen, O. Kastholm, Otto Uldum, P. Favia, P. Holck, S. Sten, S. V. Arge, Sturla Ellingvåg, V. Moiseyev, W. Bogdanowicz, Yvonne Magnusson, L. Orlando, Peter Pentz, M. Jessen, Anne Pedersen, M. Collard, D. Bradley, M. Jørkov, J. Arneborg, N. Lynnerup, Neil Price, M. T. P. Gilbert, M. T. P. Gilbert, M. Allentoft, M. Allentoft, Jan Bill, S. Sindbæk, L. Hedeager, K. Kristiansen, Rasmus Nielsen, Rasmus Nielsen, T. Werge, E. Willerslev   +97 more
semanticscholar   +1 more source

Health inequalities and outcomes following acute kidney injury: a systematic review & meta-analyses of observational studies

BMC Nephrology
Background Inequalities in health describe the uneven distribution of health outcomes that result from genetic or environmental factors. The extent to which inequalities impact on outcomes from AKI is uncertain. The aim of this systematic review and meta-
Christopher H. Grant, Anita Dahiya, Taylor Palechuk, Emilie Lambourg, Beatrix Tan, Ravindra L. Mehta, Neesh Pannu, Samira Bell   +7 more
doaj   +1 more source

The NCI-NIEHS new Cohorts for Environmental Exposures and Cancer Risk (CEECR) program

Academia Oncology
Environmental exposures are recognized risk factors for cancer etiology, but substantial gaps in knowledge remain, particularly regarding associations with emerging chemical exposures, underlying biological mechanisms of disease, and risk to ...
Somdat Mahabir, Abee Boyles, Melanie Sandquist, Curt Dellavalle, Gabriel Lai, Tram K. Lam   +5 more
doaj   +1 more source

Delivery of Interventions for Multiple Lifestyle Factors in Primary Healthcare Settings: A Narrative Review Addressing Strategies for Effective Implementation

Lifestyle Medicine
The escalating burden of lifestyle‐related diseases stands as a critical global public health challenge, contributing substantially to the prevalence of chronic conditions and a large portion of premature mortality.
Callum J. Leese, Hussain Al‐Zubaidi, Blair H. Smith   +2 more
doaj   +1 more source

Population development to help resolve and move traits in genomics-assisted breeding : OP03 [PDF]

, 2013
Plant breeding programs evolve by developing a better understanding of genetic architecture of agricultural traits and making more use of it with minimal resource diversion from mainstream genetic gain accumulation.
Glaszmann, Jean-Christophe
core  

Population genomics demystifies the defoliation phenotype in the plant pathogen Verticillium dahliae

New Phytologist, 2019
Summary Verticillium dahliae is a broad host‐range pathogen that causes vascular wilts in plants. Interactions between three hosts and specific V. dahliae genotypes result in severe defoliation.
Dan-Dan Zhang, Jie Wang, Dan Wang, Zhiqiang Kong, Lei Zhou, Geng-yun zhang, Y. Gui, Jun-Jiao Li, Jin-Qun Huang, Bao Wang, Chun Liu, C. Yin, Rui-Xing Li, Ting-Gang Li, Jin-Long Wang, D. Short, S. Klosterman, R. Bostock, K. Subbarao, Jieyin Chen, X. Dai   +20 more
semanticscholar   +1 more source