Results 131 to 140 of about 8,031,804 (248)

KLEBSIELLA PNEUMONIAE: ASPECTS OF POPULATION GENOMICS

Interdisciplinary Approaches to Medicine
Klebsiella pneumoniae is one of the causes of antimicrobial-resistant opportunistic infections. Klebsiella pneumoniae is naturally resistant to penicillins and many antimicrobials. Knowledge about the ecology, population structure, or pathogenicity of K.
Oksana Gisinger
doaj   +3 more sources

Spatiotemporal profiling reveals the impact of caloric restriction in the aging mammalian brain

Cell Reports
Summary: Caloric restriction (CR) is a well-studied intervention that extends lifespan and slows cognitive decline across species, yet the specific cell populations and molecular pathways involved remain elusive. In this study, we profiled >500,000 cells
Zehao Zhang, Alexander Epstein, Chloe Schaefer, Abdulraouf Abdulraouf, Weirong Jiang, Wei Zhou, Junyue Cao   +6 more
doaj   +1 more source

Recombination events restored the functional horned haplotypes in the offspring of polled parents

Genetics Selection Evolution
Background Breeding of genetically polled animals is a desirable approach in modern cattle husbandry for welfare and economic reasons. At least four different genetic variants associated with polledness in cattle have been identified, suggesting genetic ...
Maulik Upadhyay, Alexander Graf, Neža Pogorevc, Doris Seichter, Ingolf Russ, Stefan Krebs, Saskia Meier, Ivica Medugorac   +7 more
doaj   +1 more source

Examining the current standards for genetic discovery and replication in the era of mega-biobanks

Nature Communications, 2018
Genome-wide association studies (GWAS) have become a mainstay in genetics research to understand genotype-phenotype relationships. Following the second release of UK Biobank data and the flood of publications using these data, here the author revisits ...
J. E. Huffman
doaj   +1 more source

The impact of adverse childhood experiences on multimorbidity: a systematic review and meta-analysis

BMC Medicine
Background Adverse childhood experiences (ACEs) have been implicated in the aetiology of a range of health outcomes, including multimorbidity. In this systematic review and meta-analysis, we aimed to identify, synthesise, and quantify the current ...
Dhaneesha N. S. Senaratne, Bhushan Thakkar, Blair H. Smith, Tim G. Hales, Louise Marryat, Lesley A. Colvin   +5 more
doaj   +1 more source

How Can We Move Clinical Genomics Beyond the Hype? [PDF]

, 2011
Examines the debate over increased use of genetic testing, due in part to lax regulation, and its consequences: wasteful spending, patient harm, and health system challenges.
Michael L. Millenson
core  

Stacks: an analysis tool set for population genomics

Molecular Ecology, 2013
J. Catchen, Paul A Hohenlohe, S. Bassham, A. Amores, W. Cresko   +4 more
semanticscholar   +1 more source

Molecular Biology at the bedside: the impact of Genomics on the practice of medicine [PDF]

, 2002
Imagine being a newborn baby, discharged home after delivery, with a most unusual gift, a compact disc (CD) carrying all data on "My Genome". The parents would be most anxious to play it on their home PC. Soon, they could discover whether their child has
Felice, Alex
core  

Association between digit ratio (2D:4D) and right–left difference in 2D:4D ratio with breast cancer risk: multicentre case–control study from India

Scientific Reports
Recently, the second to fourth fingers/digits ratio (2D:4D) has been reported to be associated with breast cancer (BC). We aimed to assess whether this association exists in Indian population.
Romi Moirangthem, Aniket Patil, Garvit Chitkara, Siddhartha Kar, George Davey Smith, Rajesh Dikshit, Sharayu Mhatre   +6 more
doaj   +1 more source

Locomotion in Response to Shifting Climate Zones: Not So Fast [PDF]

, 2010
Although a species’ locomotor capacity is suggestive of its ability to escape global climate change, such a suggestion is not necessarily straightforward. Species vary substantially in locomotor capacity, both ontogenetically and within/among populations,
Feder, Martin E., Garland, Theodore, Jr., Marden, James H., Zera, Anthony J.   +3 more
core   +1 more source