Results 171 to 180 of about 5,282,511 (279)

Selection, recombination and population history effects on runs of homozygosity (ROH) in wild red deer (Cervus elaphus). [PDF]

Heredity (Edinb), 2023
Hewett AM, Stoffel MA, Peters L, Johnston SE, Pemberton JM.   +4 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Unveiling the Genomic Landscape of Yan Goose (Anser cygnoides): Insights into Population History and Selection Signatures for Growth and Adaptation. [PDF]

Animals (Basel)
Qi S, Ai Z, Cai Y, Zhang Y, Zhao W, Chen G.   +5 more
europepmc   +1 more source

The deep population history in Africa. [PDF]

Hum Mol Genet, 2021
Hollfelder N, Breton G, Sjödin P, Jakobsson M.   +3 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Human population history on the North Coast of peru from Y chromosomes and mitogenomes. [PDF]

Sci Rep
Huber LL, Arango-Isaza E, Sandoval JR, Urban M, Francalacci P, Calò C, Macholdt E, Stoneking M, Roewer L, Seidel M, Acosta O, Fujita R, Shimizu KK, Barbieri C.   +13 more
europepmc   +1 more source

Population Genetic Structure and Population History of the Biting Midge Culicoides mahasarakhamense (Diptera: Ceratopogonidae). [PDF]

Insects, 2022
Pramual P, Jomkumsing P, Wongpakam K, Vaisusuk K, Chatan W, Gomontean B.   +5 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Population History Across Timescales in an Urban Archipelago. [PDF]

Genome Biol Evol
Howell EK, Nolfo-Clements LE, Payseur BA.   +2 more
europepmc   +1 more source

Correction: Human impact on the recent population history of the elusive European wildcat inferred from whole genome data. [PDF]

BMC Genomics, 2023
Nieto-Blázquez ME, Schreiber D, Mueller SA, Koch K, Nowak C, Pfenninger M.   +5 more
europepmc   +1 more source