Results 81 to 90 of about 2,115,565 (309)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
What do Bayesian methods offer population forecasters?
, 2010 The Bayesian approach has a number of attractive properties for probabilistic forecasting. In this paper, we apply Bayesian time series models to obtain future population estimates with uncertainty for England and Wales.
Smith, Peter W.F. +4 more
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The population biology of Ligia oceanica (L.)(Crustacea: Oniscoidea) [PDF]
, 1984 The dynamics and life history of an isolated population of Ligia oceanica (L. ) inhabiting a sea-wall exposed to moderate wave action have been studied over a period of three years.
Willows, Robert I.
core
The Genetic Landscape of Kyrgyzstan: admixture and genetic history of a population from Central Asia [PDF]
, 2023 openKyrgyzstan is a Central Asia country, inhabited mainly by a Turkic ethnic group, the Kyrgyz people. It was once crossed by the ancient Silk Road, being a melting point of cultures, languages, and genes.
DE LIMA TANADA, ANNA CAROLINA EMI
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ecology and EvolutionLiriodendron was widely distributed across the Northern Hemisphere during the early to middle Miocene, but now is confined to East Asia and North America.
Yanli Cheng +4 more
doaj +1 more source
Why were New Zealand levels of life-expectation so high at the dawn of the twentieth century?
, 2002 With population ageing becoming an issue of major importance for societies in the developed countries, in both the scientific and policy communities there is widespread interest in the determinants of these structural changes.
Cheung, Jit, Pool, Ian
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Mammal diversity survey of Ko Pha-ngan in Surat Thani Province, Thailand [PDF]
ZooKeysThis study aims to survey mammal diversity on Ko Pha-ngan, located 80 km off the east peninsular coast of Surat Thani province, Thailand. Thirteen camera trap sites, 32 transects, six drift line fence traps, five mist net trap sites, and nine live trap ...
Dawn R. Cook-Price +4 more
doaj +3 more sources