Results 91 to 100 of about 2,115,565 (309)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A multilevel event history analysis of the effects of grandmothers on child mortality in a historical German population [PDF]
We analyzed data from the historic population of the Krummhörn (Ostfriesland, Germany, 1720-1874) to determine the effects of grandparents in general and grandmothers in particular on child mortality.
Eckart Voland, Jan Beise
core
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Phylogeny as population history [PDF]
The construction and use of phylogenetic trees is central to modern systematics. But it is unclear exactly what phylogenies and phylogenetic trees represent. They are sometimes said to represent genealogical relationships between taxa, between species, or simply between “groups of organisms.” But these are incompatible representational claims.
openaire +1 more source
New Zealand Regions, 1986-2001: Education and qualifications
This paper investigates changes in patterns of education and the highest qualifications people gained over the period 1986 to 2001 for the regions of New Zealand. Education is an essential element in the accumulation of human capital. Factors analysed in
Lindop, J. +3 more
core
High genetic diversity in the remnant island population of hihi and the genetic consequences of re-introduction [PDF]
The maintenance of genetic diversity is thought to be fundamental for the conservation of threatened species. It is therefore important to understand how genetic diversity is affected by the re-introduction of threatened species.
Brekke, Patricia +11 more
core +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Swedish population history [PDF]
Abstract Scandinavia, and Sweden in particular, has long held a prominent place in studies of historical demography. This is explained by the simple fact that these countries began to hold population censuses and to establish the national registration of baptisms, burials and marriages in the eighteenth century long before other European countries ...
openaire +1 more source
Procreate and cherish: A note on Australia’s abrupt shift to Pro-Natalism
After a long history of arguing that Australian governments do not intervene in the bedrooms of the nation, in 2004 the Howard Government did exactly that. Under the enthusiastic choreographing of then Treasurer Peter Costello, it implemented an explicit
Jackson, Natalie, Casey, Amina
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source

