Results 121 to 130 of about 17,498 (264)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Spectacular Nucleosynthesis from Early Massive Stars

open access: yesThe Astrophysical Journal Letters
Stars that formed with an initial mass of over 50 M _⊙ are very rare today, but they are thought to be more common in the early Universe. The fates of those early, metal-poor, massive stars are highly uncertain.
Alexander P. Ji   +41 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Hidden Population III Descendants in Ultrafaint Dwarf Galaxies

open access: yesThe Astrophysical Journal
The elusive properties of the first (Population III or Pop III) stars can be indirectly unveiled by uncovering their true descendants. To this end, we exploit our data-calibrated model for the best-studied ultrafaint dwarf galaxy (UFD), Boötes I, which ...
Martina Rossi   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

AEOS: Transport of Metals from Minihalos following Population III Stellar Feedback

open access: yesThe Astrophysical Journal
We investigate how stellar feedback from the first stars (Population III) distributes metals through the interstellar and intergalactic medium using the star-by-star cosmological hydrodynamics simulation, A eos .
Jennifer Mead   +9 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Origin of α-poor Very Metal-poor Stars

open access: yesThe Astrophysical Journal
Among very metal-poor (VMP) stars, α -poor VMP ( α -PVMP) stars that have subsolar values of [X/Fe] for Mg and other α elements are rare and are thought to have been formed from gas polluted by Type 1a supernova (SN 1a). However, recent analyses indicate
S. K. Jeena, Projjwal Banerjee
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A Semianalytic Framework of Population III and Subsequent Galaxy Formation on Cosmological N-body Simulations

open access: yesThe Astrophysical Journal
We develop a new semianalytic framework of Population (Pop) III and subsequent galaxy formation designed to run on dark matter halo merger trees. In our framework, we consider the effect of the Lyman–Werner flux from Pop III and II stars and the dark ...
Tomoaki Ishiyama, Shingo Hirano
doaj   +1 more source

Home - About - Disclaimer - Privacy