Results 141 to 150 of about 2,986,773 (268)

Population Size and Effectiveness of Selection [PDF]

Evolution, 1954
Everett R. Dempster, I. Michael Lerner
openaire   +1 more source

Evolution of Ivermectin Resistance in the Nematode Model <i>Caenorhabditis elegans</i>: Critical Influence of Population Size and Altered Emodepside Efficacy. [PDF]

Evol Appl
Hellinga J, Trubenova B, Wagner J, Borchert M, Krücken J, Regoes RR, Schulenburg H, von Samson-Himmelstjerna G.   +7 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Periodicity in Steller's eider (Polysticta stelleri) population size and density on the Arctic Coastal Plain, Alaska, revealed using generalized additive models. [PDF]

PLoS One
Osnas EE.
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Resolving sampling and population-size biases in domestication genomics supports a South Asian origin of walnuts. [PDF]

Genome Biol
Chen CJ, Pang XX, Ding YM, Zhang WP, Yang Y, Liu J, Nersesyan A, Zhang BW, Renner SS, Zhang DY, Bai WN.   +10 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Sexual Selection Associated With an Aggressive Male Phenotype Reduces Population Size and Hinders Population Recovery After Heat Stress. [PDF]

Ecol Lett
Pandey N, Porwal N, Parrett JM, Radwan J, Knell RJ, Cameron TC.   +5 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Sexual risk behaviours and population size estimation of men who have sex with men in Bhutan: a cross-sectional survey. [PDF]

BMJ Public Health
Khandu L, Hallett J, Crawford G, Leavy JE, Vujcich D, Gyeltshen T, McFarland W.   +6 more
europepmc   +1 more source