Results 61 to 70 of about 11,936 (181)

Porcine circovirus: Transcription and DNA replication

Virus Research, 2012
This review summarizes the molecular studies pertaining to porcine circovirus (PCV) transcription and DNA replication. The genome of PCV is circular, single-stranded DNA and contains 1759-1768 nucleotides. Both the genome-strand (packaged in the virus particle) and the complementary-strand (synthesized in the new host) encode viral proteins.
openaire   +2 more sources

The 2.3-Angstrom Structure of Porcine Circovirus 2 [PDF]

Journal of Virology, 2011
ABSTRACT Porcine circovirus 2 (PCV2) is a T=1 nonenveloped icosahedral virus that has had severe impact on the swine industry. Here we report the crystal structure of an N-terminally truncated PCV2 virus-like particle at 2.3-Å resolution, and the cryo-electron microscopy (cryo-EM) image reconstruction of a full-length PCV2 virus-like particle
Reza, Khayat, Nicholas, Brunn, Jeffrey A, Speir, John M, Hardham, Robert G, Ankenbauer, Anette, Schneemann, John E, Johnson   +6 more
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Establishment and Characterization of an Immortalized Porcine Oral Mucosal Epithelial Cell Line as a Cytopathogenic Model for Porcine Circovirus 2 Infection

Frontiers in Cellular and Infection Microbiology, 2019
Porcine circovirus 2 (PCV2) is a major etiological agent for porcine circovirus-associated diseases and causes enormous economic losses in domestic and overseas swine production.
Hongjie Cui, Wulong Liang, Dahui Wang, Kangkang Guo, Yanming Zhang   +4 more
doaj   +1 more source

Epidemiological investigation of porcine circovirus type 2 and its coinfection rate in Shandong province in China from 2015 to 2018

BMC Veterinary Research, 2021
Background Porcine circovirus type 2 (PCV2) is one of the crucial swine viral pathogens, caused porcine circovirus associated diseases (PCVAD). Shandong province is one of the most important pork producing areas and bears a considerable economic loss due
Zicheng Ma, Mengda Liu, Zhaohu Liu, Fanliang Meng, Hongyu Wang, Longlong Cao, Yan Li, Qiulin Jiao, Zifeng Han, Sidang Liu   +9 more
doaj   +1 more source

Development of a High‐Resolution Melting (HRM)‐Based Multiplex Real‐Time PCR Assay of PEDV, TGEV, PoRV, PDCoV, PRV, and PRRSV

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Six key viral pathogens—porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), porcine rotavirus (PoRV), porcine deltacoronavirus (PDCoV), pseudorabies virus (PRV), and porcine reproductive and respiratory syndrome virus (PRRSV)—inflict substantial economic losses on the global swine industry.
Fangshan Wang, Jing Ren, Yawen Wang, Chen Yuan, Tairan Sun, Jinhai Huang, Qinye Song, Nan-hua Chen   +7 more
wiley   +1 more source

Mechanistic Landscape and Farm to Fork Control Strategies for Streptococcus suis: An Emerging Foodborne Threat

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Streptococcus suis (S. suis) is an emerging zoonotic agent that now rivals classical food‐borne pathogens in its global clinical burden of meningitis and septic shock. Recent epidemiological syntheses covering more than 30 countries now list over 1600 laboratory‐confirmed human cases with a pooled case‐fatality of about 12%, climbing beyond 18% in East
Wangyuan Yao, Meili Chen, Hongkai Ren, Qingqing Luo, Xuyuan Wang, Md. Akhtar, Zeeshan Ahmad Bhutta, Lianci Peng, Muhammad Yasir Nawaz, Mohammad Mehedi Hasan, Md. F. Kulyar, Rendong Fang, Zhong Peng   +12 more
wiley   +1 more source

Porcine Circovirus (PCV) in pigs

, 2023
In India, pig farming is one of the most viable and lucrative animal industries, and the pork sector plays a significant role in ensuring food security. Pig diseases are frequently complicated and can result in multifactorial situations, particularly when they are respiratory illnesses brought on by the porcine circovirus.
openaire   +1 more source

Establishment of a Tetra‐Primer ARMS‐PCR Assay to Discriminate Genotypes I and II African Swine Fever Viruses

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The African swine fever virus (ASFV), particularly the genotypes I and II strains that have spread beyond Africa, continues to threaten global swine production and food security. Currently, African swine fever (ASF) control strategies rely heavily on biosecurity measures underpinned with molecular diagnostics.
Leilei Ding, Kun Xue, Tao Ren, Sihan Zhang, Weldu Tesfagaber, Zhenjiang Zhang, Feihu Guan, Jie Zhang, Yuanmao Zhu, Renqiang Liu, Fang Li, Zhigao Bu, Qianyi Zhang, Encheng Sun, Dongming Zhao, Nanhua Chen   +15 more
wiley   +1 more source

Engineered PCV2 VLPs for Antigen Delivery: A Platform for Next‐Generation Veterinary Vaccines

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The capsid (Cap) protein of porcine circovirus type 2 (PCV2) self‐assembles into virus‐like particles (VLPs) that form stable, noninfectious nanoparticles with T = 1 icosahedral symmetry. Mimicking native virion architecture, these VLPs display antigens in a highly ordered array, conferring strong immunogenicity for both humoral and cellular responses.
Peiyang Ding, Yating Liu, Chenyu Wang, Aiping Wang, Linzhu Ren   +4 more
wiley   +1 more source

IN VITRO EVALUATION OF A CHIMERIC PCV1-2 CONSTRUCT IN PORCINE KIDNEY CELLS [PDF]

Exploratory Animal and Medical Research
Porcine circovirus type 2 (PCV2) is a major causative agent of porcine circovirus-associated disease (PCVAD), responsible for significant financial losses in the swine sector.
Vikramaditya Upmanyu
doaj   +1 more source