Results 81 to 90 of about 116,066 (212)

Establishment and Characterization of an Immortalized Porcine Oral Mucosal Epithelial Cell Line as a Cytopathogenic Model for Porcine Circovirus 2 Infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Porcine circovirus 2 (PCV2) is a major etiological agent for porcine circovirus-associated diseases and causes enormous economic losses in domestic and overseas swine production.
Hongjie Cui   +4 more
doaj   +1 more source

Development of a High‐Resolution Melting (HRM)‐Based Multiplex Real‐Time PCR Assay of PEDV, TGEV, PoRV, PDCoV, PRV, and PRRSV

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Six key viral pathogens—porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), porcine rotavirus (PoRV), porcine deltacoronavirus (PDCoV), pseudorabies virus (PRV), and porcine reproductive and respiratory syndrome virus (PRRSV)—inflict substantial economic losses on the global swine industry.
Fangshan Wang   +7 more
wiley   +1 more source

Mechanistic Landscape and Farm to Fork Control Strategies for Streptococcus suis: An Emerging Foodborne Threat

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Streptococcus suis (S. suis) is an emerging zoonotic agent that now rivals classical food‐borne pathogens in its global clinical burden of meningitis and septic shock. Recent epidemiological syntheses covering more than 30 countries now list over 1600 laboratory‐confirmed human cases with a pooled case‐fatality of about 12%, climbing beyond 18% in East
Wangyuan Yao   +12 more
wiley   +1 more source

Establishment of a Tetra‐Primer ARMS‐PCR Assay to Discriminate Genotypes I and II African Swine Fever Viruses

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The African swine fever virus (ASFV), particularly the genotypes I and II strains that have spread beyond Africa, continues to threaten global swine production and food security. Currently, African swine fever (ASF) control strategies rely heavily on biosecurity measures underpinned with molecular diagnostics.
Leilei Ding   +15 more
wiley   +1 more source

Comparison of Mycoplasma hyopneumoniae and porcine circovirus 2 commercial vaccines efficacy when applied separate or combined under experimental conditions [PDF]

open access: yes, 2020
Background Mycoplasma hyopneumoniae (Mhyo) and Porcine circovirus 2 (PCV-2) are two of the most significant infectious agents causing economic losses in the weaning to slaughter period.
Pérez, Mónica   +23 more
core   +1 more source

IN VITRO EVALUATION OF A CHIMERIC PCV1-2 CONSTRUCT IN PORCINE KIDNEY CELLS [PDF]

open access: yesExploratory Animal and Medical Research
Porcine circovirus type 2 (PCV2) is a major causative agent of porcine circovirus-associated disease (PCVAD), responsible for significant financial losses in the swine sector.
Vikramaditya Upmanyu
doaj   +1 more source

Engineered PCV2 VLPs for Antigen Delivery: A Platform for Next‐Generation Veterinary Vaccines

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The capsid (Cap) protein of porcine circovirus type 2 (PCV2) self‐assembles into virus‐like particles (VLPs) that form stable, noninfectious nanoparticles with T = 1 icosahedral symmetry. Mimicking native virion architecture, these VLPs display antigens in a highly ordered array, conferring strong immunogenicity for both humoral and cellular responses.
Peiyang Ding   +4 more
wiley   +1 more source

Genomic composition and pathomechanisms of porcine circoviruses: A review

open access: yesVirulence
Porcine circovirus (PCV) belongs to the genus Circovirus within the family Circoviridae; it has the smallest genome and a complicated classification system comprising PCV1, PCV2, PCV3, and PCV4.
Yong-Yu Gao   +9 more
doaj   +1 more source

Cell tropism and entry of porcine circovirus 2

open access: yesVirus Research, 2012
Porcine circovirus 2 (PCV2) may induce reproductive failure (return to oestrus, embryonic death, mummification, weak- and stillborn piglets) and postweaning multisystemic wasting syndrome (PMWS). Furthermore, it may modulate the immunity in such a way that it aggravates the outcome of many bacterial and viral infections.
H J, Nauwynck   +6 more
openaire   +2 more sources

Detection of rampant nucleotide reversion at the origin of DNA replication of porcine circovirus type 1 [PDF]

open access: yes, 2005
Mutational analysis was conducted to investigate the involvement of the “loop-sequence” (which is flanked by a pair of 11-nucleotide inverted repeats) at the origin of DNA replication of porcine circovirus type 1 with respect to viral protein synthesis ...
Andrew K. Cheung, Cheung, Andrew K.
core   +1 more source

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