Results 91 to 100 of about 15,549 (211)

Emerging Challenges and Advances in Porcine Circovirus: A Decade in Review

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Over the past decade, porcine circoviruses (PCVs) have continued to pose a significant threat to global swine health, and pivotal discoveries have significantly reshaped our understanding of their biology and control. Extensive genomic surveillance has expanded porcine circovirus 2 (PCV2) genotyping from four to at least eight lineages, with PCV2d now ...
Jiawei Zheng, Guoqing Zhang, Peiheng Li, Linzhu Ren, Nan-hua Chen   +4 more
wiley   +1 more source

Detection of Porcine Circovirus 1/2/3 and Genetic Analysis of Porcine Circovirus 2 in Wild Boar from Jiangxi Province of China

Animals, 2022
A number of disorders that harm pig production are linked to porcine circoviruses, including PCV2. PCV2 infection is a substantial contributor to porcine-circovirus-associated illnesses (PCAS) and the post-weaning multi-systemic wasting syndrome (PMWS), which have a significant negative economic impact on pig production. Additionally, PCV infection has
Xifeng Hu, Zheng Chen, Yu Li, Zhen Ding, Qinghua Zeng, Tong Wan, Huansheng Wu   +6 more
openaire   +3 more sources

Apoptosis Triggered by ORF3 Proteins of the Circoviridae Family

Frontiers in Cellular and Infection Microbiology, 2021
Apoptosis, a form of the programmed cell death, is an indispensable defense mechanism regulating cellular homeostasis and is triggered by multiple stimuli.
Yanting Zhang, Yanting Zhang, Yanting Zhang, Xingcui Zhang, Xingcui Zhang, Xingcui Zhang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Mingshu Wang, Mingshu Wang, Mingshu Wang, Zhongqiong Yin, Juan Huang, Juan Huang, Juan Huang, Renyong Jia, Renyong Jia, Renyong Jia   +18 more
doaj   +1 more source

Establishment and Evaluation of a Multicolor Latex Microsphere‐Based Lateral Flow Immunoassay for the Simultaneous Detection of Antibodies Against African and Classical Swine Fever Viruses

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF), a highly fatal disease often termed the “number one killer” of pigs, presents clinical symptoms indistinguishable from classical swine fever (CSF), such as fever, diarrhea, and vomiting, complicating on‐site differential diagnosis.
Jie Chen, Zhengwang Shi, Yi Ru, Juncong Luo, Qianqian Yang, Yage Xie, Lin Wang, Jing Zhou, Xiaoyang Zhang, Juanjuan Wei, Yuqian Zhu, Hong Tian, Haixue Zheng, Nan-hua Chen   +13 more
wiley   +1 more source

Phylogenetic analysis of porcine circovirus type 3 and porcine circovirus type 2 in China detected by duplex nanoparticle-assisted PCR

Infection, Genetics and Evolution, 2018
Porcine circovirus 2 causes different clinical syndromes resulting in a significant economic loss in the pork industry and PCV3 infection was mainly distributed in the pig herds exhibiting PDNS and reproductive failure symptoms and was widely prevalent in the swine population in several states of the USA.
Lingling, Zhang, Yakun, Luo, Lin, Liang, Jinxiang, Li, Shangjin, Cui   +4 more
openaire   +2 more sources

Establishment and Application of a Novel Protein Microarray for Serological Detection and Differentiation of Senecavirus A

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Senecavirus A (SVA) is an emerging swine pathogen that causes vesicular disease, which presents clinically indistinguishable signs from other vesicular diseases. To enable differentiation of infected from vaccinated animals (DIVA), we developed a novel protein microarray for dual serological detection of antibodies against SVA structural (VP2‐VP3‐VP1 ...
Dexin Li, Junhua Deng, Zenglin Wang, Yunjing Zhang, Yufang Li, Liying Hao, Kegong Tian, Xiangdong Li, Linzhu Ren   +8 more
wiley   +1 more source

Design of B‐Cell Multi‐Epitope Subunit Vaccines Against Glaesserella parasuis by Reverse Vaccinology: An In Silico and In Vivo Study

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Glässer’s disease caused by Glaesserella parasuis (GPS) is a severe disease that results in substantial economic losses to the swine industry worldwide. Here we describe a multiepitope vaccine cocktail (MEVC) that was designed using reverse vaccinology and immunoinformatics. The MEVC was comprised of three multiepitope subunits (MESs, designated as TB,
Yan Gong, Na Li, Ziheng Li, He Wang, Di Zhang, Hong Chu, Zhichao Lu, Aiqing Jia, Fengyang Li, Liancheng Lei, Zhong Peng   +10 more
wiley   +1 more source

Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Viral diseases are a major threat to human and animal health, as illustrated by recent pandemics like COVID‐19 and African swine fever (ASF). Timely, accurate detection of viral infections is critical for effective disease control. Among diverse diagnostic techniques, lateral flow immunoassay (LFIA) has become a widely used on‐site testing tool, owing ...
Quanyu Ren, Yan Wang, Haoyuan Ma, Jialiang Xie, Jianyou Jin, Rumeng Tian, Hao Yu, Xu Gao, Nanhua Chen   +8 more
wiley   +1 more source

A Natural Recombinant NADC30‐Like PRRSV Strain in China: Intersection of CH‐1a, QYYZ, and JXA1 Lineages

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine reproductive and respiratory syndrome virus (PRRSV) remains a major threat to global swine production. In this study, a novel strain (PRRSV‐AH1) was isolated during a respiratory disease outbreak at a commercial swine operation in Anhui Province, China. Viral replication in MARC‐145 cells was confirmed by observing cytopathic effects (CPEs) and
Heng Zhang, Chengxin Zhang, Yingru Ma, Qin Zhao, Ximei Wang, Qing Pan, Yani Sun, Nan-hua Chen   +7 more
wiley   +1 more source

A Novel In‐Cell ELISA With Superior Sensitivity and Specificity for the Detection of African Swine Fever Virus‐Specific IgM and IgG Antibodies

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF), a high‐profile transboundary animal disease caused by ASF virus (ASFV), imposes a devastating impact on the global swine industry. Given that vaccines are still under development, including field evaluations, early detection of ASFV is crucial for effective disease control and mitigation.
Ping Wu, Aric J. McDaniel, Yelitza Y. Rodríguez, Vivian O’Donnell, Wei Jia, Nan-hua Chen   +5 more
wiley   +1 more source