Results 91 to 100 of about 29,352,683 (204)

Divergent Effects of Circoviridae Capsid Proteins on Type I Interferon Signaling

open access: yesPathogens
Viruses in the Circoviridae family can infect mammals and birds. Porcine circovirus type 2 (PCV2) significantly affects the livestock industry by causing porcine circovirus-associated diseases, such as postweaning multisystem wasting syndrome ...
Anon H. Kosaka   +7 more
doaj   +1 more source

Emergence of a Novel CRESS‐DNA Virus Associated with Swine Reproductive Failure in China

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The continuous emergence of circular Rep‐encoding single‐stranded (CRESS) DNA viruses across diverse hosts has been closely associated with the occurrence of severe diseases. Four circoviruses within the genus Circovirus have been identified in pigs, including porcine circovirus Type 1 (PCV1), PCV2, PCV3, PCV4, and PCV5.
Xianhui Liu   +13 more
wiley   +1 more source

Molecular Detection and Phylogenetic Analysis of Selected Viral Pathogens in Wild Boar Populations of Russia

open access: yesViruses
The distribution and genetic diversity of economically significant pathogens, including porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), porcine circovirus type 3 (PCV3), and porcine parvovirus 1 (PPV1 ...
Valentina Rykova   +6 more
doaj   +1 more source

Porcine circovirus type 2 exploits JNK-mediated disruption of tight junctions to facilitate Streptococcus suis translocation across the tracheal epithelium

open access: yesVeterinary Research, 2020
Porcine circovirus type 2 (PCV2) is considered as the primary pathogen of porcine circovirus-associated disease (PCVAD), which results in significant economic losses worldwide.
Qing Wang   +4 more
doaj   +1 more source

Emerging Challenges and Advances in Porcine Circovirus: A Decade in Review

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Over the past decade, porcine circoviruses (PCVs) have continued to pose a significant threat to global swine health, and pivotal discoveries have significantly reshaped our understanding of their biology and control. Extensive genomic surveillance has expanded porcine circovirus 2 (PCV2) genotyping from four to at least eight lineages, with PCV2d now ...
Jiawei Zheng   +4 more
wiley   +1 more source

Design of B‐Cell Multi‐Epitope Subunit Vaccines Against Glaesserella parasuis by Reverse Vaccinology: An In Silico and In Vivo Study

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Glässer’s disease caused by Glaesserella parasuis (GPS) is a severe disease that results in substantial economic losses to the swine industry worldwide. Here we describe a multiepitope vaccine cocktail (MEVC) that was designed using reverse vaccinology and immunoinformatics. The MEVC was comprised of three multiepitope subunits (MESs, designated as TB,
Yan Gong   +10 more
wiley   +1 more source

Hsp70 positively regulates porcine circovirus type 2 replication in vitro [PDF]

open access: yes, 2013
The Hsp70 chaperone plays a central role in multiple processes within cells. Porcine circovirus type 2 (PCV2) is the essential causal agent of post-weaning multisystemic wasting syndrome (PMWS), which has spread worldwide.
Liu, Jie   +6 more
core   +1 more source

CO-INFECTIONS OF CLASSICAL SWINE FEVER VIRUS, PORCINE SAPELOVIRUS AND PORCINE CIRCOVIRUS 2 IN DIARRHEIC PIGLETS: EVIDENCE FROM KARNATAKA, INDIA [PDF]

open access: yesExploratory Animal and Medical Research
Suckling and weaned piglets suffering from gastrointestinal disorders often develop diarrhea due to viral co-infections. Classical swine fever virus, porcine sapelovirus, and porcine circovirus type 2 are important pathogens that pose a threat to the ...
Sharanagouda Patil
doaj   +1 more source

Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Viral diseases are a major threat to human and animal health, as illustrated by recent pandemics like COVID‐19 and African swine fever (ASF). Timely, accurate detection of viral infections is critical for effective disease control. Among diverse diagnostic techniques, lateral flow immunoassay (LFIA) has become a widely used on‐site testing tool, owing ...
Quanyu Ren   +8 more
wiley   +1 more source

A Novel Attenuated NADC30‐Like PRRSV Vaccine Candidate Provides Cross‐Protection Against Homologous and Heterologous Viral Challenge

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) is one of the major pathogens threatening the global swine industry and causes enormous economic losses annually. Vaccination remains one of the most important strategies for the prevention and control of PRRSV infection.
Heng Zhang   +10 more
wiley   +1 more source

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