Results 71 to 80 of about 1,678 (165)

PCV2 infection aggravates OTA-induced immunotoxicity in vivo and in vitro

Ecotoxicology and Environmental Safety, 2022
Ochratoxin A (OTA), frequently existing in the food and feeds, could induce immunotoxicity. Porcine circovirus type 2 (PCV2), as a primary causative agent of porcine circovirus–associated disease, also could induce immunosuppression. However, it is still
Fang Gan, Lili Hou, Haibin Xu, Yunhuan Liu, Xingxiang Chen, Kehe Huang   +5 more
doaj   +1 more source

Concomitant Infection With Porcine circovirus 2 and Porcine Epidemic Diarrhea Virus Does Not Increase Enteritis Severity in Experimentally Infected Weaned Piglets

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Background Young pigs are often coinfected with porcine circovirus 2 (PCV2) and porcine epidemic diarrhea virus (PEDV). This study aimed to determine the impact of coinfection of pigs with PCV2 and PEDV. Forty 16‐day‐old crossbred mixed‐sex piglets were assigned to four groups (n = 10/group, NEG‐CONTROL, PCV2‐CONTROL, PCV2+PEDV, and PEDV‐CONTROL).
Priscilla F. Gerber, Jianqiang Zhang, Andrew Noel, Bin Wang, Yaowei Huang, Patrick G. Halbur, Tanja Opriessnig, Jizong Li   +7 more
wiley   +1 more source

Engineered PCV2 VLPs for Antigen Delivery: A Platform for Next‐Generation Veterinary Vaccines

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The capsid (Cap) protein of porcine circovirus type 2 (PCV2) self‐assembles into virus‐like particles (VLPs) that form stable, noninfectious nanoparticles with T = 1 icosahedral symmetry. Mimicking native virion architecture, these VLPs display antigens in a highly ordered array, conferring strong immunogenicity for both humoral and cellular responses.
Peiyang Ding, Yating Liu, Chenyu Wang, Aiping Wang, Linzhu Ren   +4 more
wiley   +1 more source

Identification of Putative ORF5 Protein of Porcine Circovirus Type 2 and Functional Analysis of GFP-Fused ORF5 Protein. [PDF]

PLoS ONE, 2015
Porcine circovirus type 2 (PCV2) is the essential infectious agent responsible for causing porcine circovirus-associated diseases in pigs. To date, eleven RNAs and five viral proteins of PCV2 have been detected.
Qizhuang Lv, Kangkang Guo, Han Xu, Tao Wang, Yanming Zhang   +4 more
doaj   +1 more source

Characterisation of porcine circovirus type 2 in porcine circovirus disease cases in England and Wales [PDF]

, 2018
Confirmed cases of porcine circovirus disease (PCVD) in Great Britain have shown a steady decline since the availability of porcine circovirus type 2 (PCV2) vaccines. However, PCVD is still occasionally diagnosed.
Werling, D, Sylvia S Grierson, Williamson, S, Bidewell, C, Grierson, S S, Susanna Williamson, Dirk Werling, Cornelia Bidewell   +7 more
core   +1 more source

Development of Magnetic Particle–Based Chemiluminescence Immunoassays for Detecting PCV2 VLP‐ and Rep‐Specific Antibodies and Their Combined Use for Immune Evaluation and Replication‐Associated Exposure Assessment

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine circovirus 2 (PCV2) remains a major swine pathogen, and interpretation of capsid protein (Cap)–based serology is challenging in vaccinated populations because vaccine‐induced Cap antibodies overlap with replication‐associated serological signals.
Mingxi Gou, Xiaoqing Song, Jie Fan, Zhixiong Chen, Zihao Kuang, Mengyao Lu, Zhongxin Fan, Meng Ge, Zhong Peng   +8 more
wiley   +1 more source

Cross-Sectional Study on the Sero- and Viral Dynamics of Porcine Circovirus Type 2 in the Field

Vaccines, 2020
Porcine circovirus-associated diseases (PCVADs) cause considerable economic losses in industrial pork production in the field. To minimize the economic losses due to PCVAD, porcine circovirus type 2 (PCV2) vaccines have been developed, and there is ...
Chao-Nan Lin, Ni-Jyun Ke, Ming-Tang Chiou   +2 more
doaj   +1 more source

Utilizing vaccination for Porcine Circovirus Type 2 as a tool to aid elimination of PCV2 from swine populations [PDF]

, 2011
A total of 928 pigs from the Swine Teaching and Research Centers at Michigan State University (MSU) and Kansas State University (KSU) and a Kansas commercial farm were used during a 3-year study to determine whether circovirus vaccination influenced ...
Hesse, Richard A, Rowland, Raymond R. R., Potter, M. L., Steven C Henry, M L Potter, Nietfeld, Jerome C., Rowland, Raymond R, Dritz, Steven S, R O Bates, Potter, M L, Straw, B. E., Dritz, Steven S., Richard D Oberst, A Fuller, Oberst, Richard D., Lisa M Tokach, Jerome C Nietfeld, Henry, Steven C., Hays, Michael P, Fuller, A, Bates, R. O., Oberst, Richard D, Nietfeld, Jerome C, Richard A Hesse, Henry, Steven C, Straw, B E, Fuller, A., Michael P Hays, Raymond R Rowland, Steven S Dritz, B E Straw, Hesse, Richard A., Tokach, Lisa M., Tokach, Lisa M, Hays, Michael P., Bates, R O   +35 more
core   +1 more source

Emergence of a Novel CRESS‐DNA Virus Associated with Swine Reproductive Failure in China

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The continuous emergence of circular Rep‐encoding single‐stranded (CRESS) DNA viruses across diverse hosts has been closely associated with the occurrence of severe diseases. Four circoviruses within the genus Circovirus have been identified in pigs, including porcine circovirus Type 1 (PCV1), PCV2, PCV3, PCV4, and PCV5.
Xianhui Liu, Yixuan Li, Jian Xiao, Xinming Zhang, Yilong Liu, Zan li, Lin Wang, Leyi Zhang, Yanling Liu, Pengshuai Liang, Zheng Xu, Yebing Liu, Changxu Song, Linzhu Ren   +13 more
wiley   +1 more source

Divergent Effects of Circoviridae Capsid Proteins on Type I Interferon Signaling

Pathogens
Viruses in the Circoviridae family can infect mammals and birds. Porcine circovirus type 2 (PCV2) significantly affects the livestock industry by causing porcine circovirus-associated diseases, such as postweaning multisystem wasting syndrome ...
Anon H. Kosaka, Chen-Yu Huang, Zih-Ying Lu, Hua-Zhen Hsing, Amonrat Choonnasard, Rissar Siringo Ringo, Kuo Pin Chuang, Akatsuki Saito   +7 more
doaj   +1 more source