Results 41 to 50 of about 9,681 (125)

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Development of a Novel Polyleucine‐Based Immunopotentiator for Subunit Vaccines Against Group A Streptococcus

Small, Volume 22, Issue 22, 17 April 2026.
Self‐assembling amphiphilic peptide L15K6 is used as a novel immunoadjuvant for the development of a Group A Streptococcus vaccine. Robust antigen‐specific IgG responses are generated and manage to kill isolated strains of Group A Streptococcus. Cellular and bulk RNA sequencing data reveals that L15K6 regulates immune responses potentially through TLR ...
Lantian Lu, Jazmina L. Gonzalez Cruz, Rabina Giri, Yuexiao Zhang, Sahra Bashiri, Leslie C. Domínguez Cadena, Shuhang Li, Zeinab G. Khalil, Waleed M. Hussein, Jingwen Wang, Jolynn Kiong, Xuehan Lu, Jiahui Zhang, Miao Lu, Wenbin Huang, Wei Yang Kong, Ummey Jannatun Nahar, Prashamsa Koirala, Zhong Guo, Patricia Walden, Antje Blumenthal, Jakob Begun, Kirill Alexandrov, Istvan Toth, Rachel J. Stephenson, Mariusz Skwarczynski   +25 more
wiley   +1 more source

Construction and immunogenicity evaluation of a bivalent nanoparticle based on mi3 displaying porcine circovirus type 2 and type 3 capsid proteins

Frontiers in Veterinary Science
Porcine circovirus type 2 (PCV2) and type 3 (PCV3) pose severe threats to swine health worldwide. PCV2 field strains continuously mutate with the co-circulation of multiple genotypes, resulting in potential immune escape from existing vaccines.
Baishi Lei, Baishi Lei, Baishi Lei, Jiale Du, Yiran Li, Yuchuan Yang, Peng Chen, Longhai Ji, Wuchao Zhang, Wuchao Zhang, Yunhang Zhang, Yunhang Zhang, Kuan Zhao, Kuan Zhao, Wanzhe Yuan, Wanzhe Yuan   +15 more
doaj   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Establishment and preliminary application of duplex fluorescence quantitative PCR for porcine circoviruses type 2 and type 3

Heliyon
Porcine circovirus types 2 (PCV2) and 3 (PCV3) are the two most prevalent porcine circoviruses in China, all of which can infect swine herds and cause serious diseases. To detect coinfection with PCV2 and PCV3, primers and probes for duplex PCV2 and PCV3
Yong-Yu Gao, Qian Wang, Shuang Zhang, Jian Zhao, Di Bao, Han Zhao, Kai Wang, Gui-Xue Hu, Feng-Shan Gao   +8 more
doaj   +1 more source

A novel kirkovirus may be associated with equine gastrointestinal disease

Equine Veterinary Journal, Volume 58, Issue 2, Page 414-422, March 2026.
Abstract Background Many cases of equine enterocolitis are suspected to be infectious in nature, but no pathogen is identified in many cases. Objectives Perform next‐generation sequencing on faeces collected from cases of equine enterocolitis for the presence of novel viruses and determine if an identified novel virus is associated with cases of equine
Lillian M. B. Haywood, Ava Clark, Ben Hause, Breanna Sheahan   +3 more
wiley   +1 more source

Pathogenesis and Transmission of a Reassorted H1 Influenza A Virus Detected in North American Swine

Influenza and Other Respiratory Viruses, Volume 20, Issue 2, February 2026.
ABSTRACT Background The USDA influenza A virus in swine national surveillance plan identified an increase in the detection frequency of a group of swine 1A.1.1.3 hemagglutinin (HA) clade viruses. This change was associated with reassortment events that resulted in new neuraminidase (NA) gene pairings.
Débora B. Goulart, Carine K. Souza, Giovana C. Zanella, Celeste A. Snyder, Janice C. Zanella, Alexey Markin, Bailey Arruda, Tavis K. Anderson, Amy L. Baker   +8 more
wiley   +1 more source

Development of a multiplex PCR to detect and discriminate porcine circoviruses in clinical specimens

BMC Infectious Diseases, 2019
Background A diagnostic method to simultaneously detect and discriminate porcine circovirus type 1 (PCV1), porcine circovirus type 2 (PCV2) and porcine circovirus type 3 (PCV3) in clinical specimens is imperative for the differential diagnosis and ...
Keli Yang, Zuwu Jiao, Danna Zhou, Rui Guo, Zhengying Duan, Yongxiang Tian   +5 more
doaj   +1 more source

A Novel Technique for Constructing Infectious Cloning of Type 3 Porcine Circovirus

Frontiers in Microbiology, 2020
Porcine circovirus type 3 (PCV3), which currently lacks effective preventive measures, has caused tremendous economic losses to the pig husbandry.
Zaixue Jiang, Jiajun Wu, Mei Jiang, Yilun Xie, Wandi Bu, Canbin Liu, Guihong Zhang, Manlin Luo   +7 more
doaj   +1 more source

First Molecular Detection of Torque Teno Canis Virus in Apparently Healthy Dogs in Southern Italy

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
•Torque teno canis virus has been detected in dogs from southern Italy. •Detection of TTCaV DNA was more frequent in dogs with an altered faecal score, mixed‐breed and belonging to kennels. ABSTRACT Background Torque teno viruses are viruses with unclear pathogenic potential, as conflicting evidence has classified this family of viruses as harmless and
Gianmarco Ferrara, Ugo Pagnini, Francesco Origgi, Serena Montagnaro   +3 more
wiley   +1 more source