Results 101 to 110 of about 1,933 (170)

Development of monoclonal antibodies and serological assays including indirect ELISA and fluorescent microsphere immunoassays for diagnosis of porcine deltacoronavirus [PDF]

open access: yes, 2016
BACKGROUND: A novel porcine deltacoronavirus (PDCoV), also known as porcine coronavirus HKU15, was reported in China in 2012 and identified in the U.S. in early 2014. Since then, PDCoV has been identified in a number of U.S.
Aaron Singrey   +8 more
core   +1 more source

Viral gastroenteritis in pigs: current knowledge and challenges [PDF]

open access: yes, 2020
Virusni gastroenteritisi u svinja predstavljaju kontinuirani izazov za uzgajivače svinja, kako sa stajališta zdravstvenog upravljanja stadom, tako i sa stajališta primjene odgovarajućih biosigurnosnih mjera.
Alen Kovačević   +3 more
core   +2 more sources

Design of Mucosal Vaccines Against Swine Enteric Coronaviruses: From Antigen Delivery to Immune Activation

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Swine enteric coronaviruses (SeCoVs) cause acute enteritis and high mortality in neonatal piglets, posing a significant threat to the swine industry. Injectable vaccines often fail to induce effective mucosal immunity, and their efficacy is further compromised by maternally derived antibodies.
Qihao Pan   +14 more
wiley   +1 more source

Porcine epidemic diarrhoea: new insights into an old disease [PDF]

open access: yes
[EN] Porcine epidemic diarrhea (PED) is an enteric disease in swine caused by an alphacoronavirus. It affects swine of all ages causing acute diarrhoea and can lead to severe dehydration and death in suckling piglets.
Argüello Rodríguez, Héctor   +6 more
core   +1 more source

Celastrol Inhibits Porcine Epidemic Diarrhea Virus Replication by Promoting ROS‐Mediated Apoptosis

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Porcine epidemic diarrhea virus (PEDV) causes acute, highly contagious enteric disease in pigs, leading to severe economic losses, particularly due to high mortality in suckling piglets. Currently, no specific antiviral drugs are available. In this study, we evaluated the anti‐PEDV potential of celastrol, a natural triterpenoid derived from ...
Junhai Zhu   +8 more
wiley   +1 more source

A novel host restriction factor MRPS6 mediates the inhibition of PDCoV infection in HIEC-6 cells [PDF]

open access: yes
IntroductionPorcine deltacoronavirus (PDCoV) is a zoonotic pathogen with a global distribution, capable of infecting both pigs and humans. To mitigate the risk of cross-species transmission and potential outbreaks, it is crucial to characterize novel ...
Chang Li   +14 more
core   +1 more source

Genetic and Pathogenic Characterization of a Porcine Deltacoronavirus Strain Isolated in Zhejiang Province, China

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Porcine deltacoronavirus (PDCoV) has emerged as a significant pathogen in swine, affecting animal health and posing potential risks for cross‐species transmission. In this study, we successfully isolated a PDCoV strain named HZYH‐2019 from the feces of diarrheal sows in Zhejiang Province, China.
Ya-Qing Zhang   +8 more
wiley   +1 more source

Severe Diarrhea Outbreaks in Newborn Piglets in China Associated With Porcine Rotavirus B

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Rotavirus B (RVB) is among the enteric pathogens that can cause gastroenteritis in humans and various animals. However, severe diarrhea in newborn piglets has rarely been reported to be linked to porcine RVB (PoRVB). From 2023 to 2024, outbreaks of newborn piglet diarrhea with 20%–50% morbidity and 4%–10% mortality occurred in three herds situated in ...
Mingkai Sun   +10 more
wiley   +1 more source

Development of an Indirect ELISA Based on the PEDV S Protein and Evaluation of Its Correlation With Neutralizing Antibody and Immune Protection

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Porcine epidemic diarrhea virus (PEDV) is an enteric coronavirus that infects pigs of all ages. Notably, neonatal piglets (≤7 days old) in naïve herds can experience case fatality rates approaching 100%, with hallmark clinical signs of vomiting, diarrhea, and dehydration, thereby representing a major threat to swine herd health. Serum PEDV‐specific IgG
Guangming Ma   +7 more
wiley   +1 more source

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