Results 111 to 120 of about 112,162 (149)

The cholesterol metabolite 25-hydroxycholesterol suppresses porcine deltacoronavirus via lipophagy inhibition and mTORC1 modulation

Veterinary Research
25-Hydroxycholesterol (25HC) is a hydroxylated cholesterol with multiple antiviral activities, however, little is known about the mechanisms by which 25HC correlates antiviral ability with lipid droplet (LD) dynamic balance to ensure cholesterol ...
Jia-lu Zhang, Xue-fei Wang, Jia-lin Li, Cong Duan, Jiu-feng Wang   +4 more
doaj   +1 more source

A novel nanoparticle vaccine, based on S1-CTD, elicits robust protective immune responses against porcine deltacoronavirus

Journal of Virology
Porcine deltacoronavirus (PDCoV), an emerging swine pathogen causing severe enteric disease in piglets, poses cross-species transmission risks, including humans.
Qing He, Yawen Zou, Beilei Yu, Qian Yuan, Chenguang Meng, Chenxuan Du, Zhiyong Wang, Jiahao Lian, Shile Luo, Siyu Cao, Wenbing Yang, Dantong Li, Hongyu Lei, Yang Zhan, Wenfeng Zhou, Yi Yang, Naidong Wang   +16 more
doaj   +1 more source

A novel strain of porcine deltacoronavirus in Vietnam

, 2018
Two porcine deltacoronavirus (PDCoV) strains(Binh21 and HaNoi6) were isolated from two pig farmsin North Vietnam. Phylogenetic analysis of the completegenomes and the Spike and Membrane genes revealed thatthe two Vietnam PDCoVs belong to the same lineage
Van Phan Le...[et al.]
core  

Accurate detection of porcine deltacoronavirus infection and the importance of antibody stability in diagnostic specimens [PDF]

Porcine deltacoronavirus (PDCoV) is an enveloped, singled-stranded, positive-sense RNA virus that belongs to the family Coronaviridae, subfamily Coronavirinae and genus Deltacoronavirus.
Yen, Lu
core  

Genetic and Evolutionary Analysis of Porcine Deltacoronavirus in Guangxi Province, Southern China, from 2020 to 2023

Porcine deltacoronavirus (PDCoV) has shown large-scale global spread since its discovery in Hong Kong in 2012. In this study, a total of 4897 diarrheal fecal samples were collected from the Guangxi province of China from 2020 to 2023 and tested using RT ...
Yeheng Gao, Feng Long, Shuping Feng, Yan Ma, Wenchao Sun, Biao Li, Yuwen Shi, Kaichuang Shi, Yanwen Yin   +8 more
core   +1 more source

DEAD-box RNA helicase 21 interacts with the nucleocapsid protein and inhibits porcine deltacoronavirus infection through upregulation of interferon responses. [PDF]

J Virol
Zhang N, Xu Y, Chen Y, Ma M, Lai W, Zhong S, Cai G, Wang T, Li B, Peng Q, Jiang H.   +10 more
europepmc   +1 more source

Porcine deltacoronavirus nucleocapsid protein inhibits RIG-I signaling pathway by suppressing G3BP1-mediated stress granules formation. [PDF]

Virulence
Guo M, Hu Y, Wang D, Tang Y, Yuan J, Shi C, Zu S, Wei Z.   +7 more
europepmc   +1 more source

Construction and Immunogenicity Evaluation of a Ferritin-Based Nanoparticle Vaccine Displaying the PDCoV Spike Receptor-Binding Domain. [PDF]

Vet Sci
Cao S, Nie N, Zhang L, Chen C, Zhou M, Zhu S.   +5 more
europepmc   +1 more source

Development of colloidal gold and carbon immunochromatographic strips for rapid detection of PDCoV. [PDF]

iScience
Hao C, Xu M, Bu T, Zhang B, Ran Z, Niu X, Chen Z, Jin X, Zhang Y, Wei Z, Zhang H.   +10 more
europepmc   +1 more source

Monoclonal antibodies target conserved S1^B epitopes across deltacoronaviruses to inhibit porcine deltacoronavirus infection. [PDF]

mBio
Zhou J, Jing R, Zhang M, Liu C, Li Y, Zhu H, Du W, Jongkaewwattana A, Bosch BJ, Peng G, He Q, Zhang M, Li W.   +12 more
europepmc   +1 more source