Results 91 to 100 of about 112,162 (149)

RNA G‐Quadruplexes in the Porcine Deltacoronavirus Genome: Structural Regulation and Therapeutic Targeting for Antiviral Strategies

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine deltacoronavirus (PDCoV) is an emerging enteric coronavirus that poses a considerable risk to swine production worldwide. G‐quadruplexes (G4s) are noncanonical nucleic acid secondary structures known to regulate critical steps of viral life cycles in multiple viruses; however, the existence and biological role of RNA G4s (RG4s) in PDCoV remain ...
Jiajing Guo   +6 more
wiley   +1 more source

Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Viral diseases are a major threat to human and animal health, as illustrated by recent pandemics like COVID‐19 and African swine fever (ASF). Timely, accurate detection of viral infections is critical for effective disease control. Among diverse diagnostic techniques, lateral flow immunoassay (LFIA) has become a widely used on‐site testing tool, owing ...
Quanyu Ren   +8 more
wiley   +1 more source

A Novel Adjuvant System for High‐Efficiency Subunit Vaccines Against Porcine Deltacoronavirus

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Summary The immunopotentiation efficacy of polydimethyl diallyl ammonium chloride (pDMDAAC) nanoparticles (NPs) as an adjuvant for the spike (S) protein subunit vaccine of porcine deltacoronavirus (PDCoV) was investigated, with particular emphasis on the combination of the NPs with the STING agonist cGAMP.
Shuangyuan Xu   +9 more
wiley   +1 more source

Porcine Enteric Coronaviruses: Origins, Global Spread, Transmission Pathways and Pathogenesis

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine enteric coronaviruses (CoVs) constitute a persistent and evolving threat to global pig production due to their high transmissibility, environmental stability and capacity for rapid international dissemination. Historically, transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhoea virus (PEDV) have been the most significant ...
Héctor Puente   +4 more
wiley   +1 more source

Celastrol Suppresses Porcine Deltacoronavirus Replication by Modulating Endoplasmic Reticulum Stress‐Associated Ca2+ Balance

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine deltacoronavirus (PDCoV) infection causes watery diarrhea and even death in neonatal piglets, leading to substantial economic losses. Meanwhile, emerging evidence indicates the potential risk of PDCoV to threaten human health and public safety. However, the effective vaccines or medicines are deficient.
Jialu Zhang   +10 more
wiley   +1 more source

Emergence of Escherichia coli Hybrid Pathotype ETEC/STEC: A Macroepidemiological Approach of Molecular Characterization in the United States Swine Population

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Escherichia coli–associated diseases continue to be a significant concern in swine health. Disease may occur when E. coli strains harbor specific virulence factors. The combination of virulence factors detected in a single isolate forms a virotype, which can be grouped into pathotypes based on mechanisms of pathogenicity. This study compiled E.
Elisa De Conti   +54 more
wiley   +1 more source

Complete Genome Sequences of Porcine Deltacoronavirus Strains DH1/2016 and DH2/2016 Isolated in South Korea

open access: yes, 2017
Two porcine deltacoronavirus (PDCoV) strains, named DH1/2016 and DH2/2016, were isolated from feces of piglets which had severe watery diarrhea symptoms.
B K Park   +17 more
core   +1 more source

Molecular Epidemiology and Pathogenicity Evaluation of Porcine Teschovirus in Tibetan Pigs on the Qinghai–Tibet Plateau of China

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine teschovirus (PTV) is the causative agent of porcine diarrhea and multisystem disorder and poses a global threat to the health of domestic pigs. However, its epidemic and pathogenic characteristics in Tibetan pigs, which are a unique indigenous breed in the Qinghai–Tibet Plateau of China, remain largely unexplored.
Haohao Lu   +8 more
wiley   +1 more source

Porcine Deltacoronavirus Utilizes Sialic Acid as an Attachment Receptor and Trypsin Can Influence the Binding Activity

open access: yes, 2021
Porcine deltacoronavirus (PDCoV) is a novel coronavirus that causes diarrhea in nursing piglets. Studies showed that PDCoV uses porcine aminopeptidase N (pAPN) as an entry receptor, but the infection of pAPN-knockout cells or pigs with PDCoV revealed ...
Shaopo Zu   +5 more
core   +1 more source

Coinfection and nonrandom recombination drive the evolution of swine enteric coronaviruses

open access: yesEmerging Microbes and Infections
Coinfection with multiple viruses is a common phenomenon in clinical settings and is a crucial driver of viral evolution. Although numerous studies have demonstrated viral recombination arising from coinfections of different strains of a specific species,
Jiahui Guo   +8 more
doaj   +1 more source

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