Results 71 to 80 of about 1,933 (170)

Coronaviruses: a review of their properties and diversity [PDF]

, 2020
Human coronaviruses, which hitherto were causative agents of mild respiratory diseases of man, have recently become one of the most important groups of pathogens of humans the world over. In less than two decades, three members of the group, severe acute
Fagbami, A.H., Joseph, A.A.
core   +2 more sources

Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy [PDF]

, 2022
This book is a compendium of scientific articles submitted to a Special Issue of International Journal of Molecular Sciences, fostered by MDPI and curated by Dr. Annamaria Sandomenico and Dr. Menotti Ruvo from the Institute of Biostructure and Bioimaging

core   +1 more source

Discovery of Cetaben as a Novel Antiviral Agent Against Porcine Epidemic Diarrhea Virus From a Cholesterol‐Lowering Compound Library

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The devastating impact of porcine epidemic diarrhea virus (PEDV) on the global swine industry underscores an urgent need for effective antiviral therapies. Drug repurposing presents a promising strategy to accelerate the development of such treatments.
Yaqin Li, Panpan Qin, Kaiqi Zhang, Ningning Ma, Tianliang Wang, Zilu Chen, Yixin Yuan, Dongliang Li, Linyang Yu, Wentao Li, Wenjuan Du, Yongtao Li, Jianchao Wei   +12 more
wiley   +1 more source

GSDMD and GSDME exhibit distinct roles in enteric coronavirus PDCoV-induced pyroptosis and inflammatory responses

Journal of Virology
Porcine deltacoronavirus (PDCoV), an emerging enteric coronavirus with zoonotic potential, typically causes intestinal villous epithelial cell damage with inflammation.
Chenyu Li, Yuting Shi, Chunying Xie, Kaiqi Duan, Tong Ding, Xiangfei Xu, Liurong Fang, Yanrong Zhou, Shaobo Xiao   +8 more
doaj   +1 more source

Porcine Deltacoronavirus-like Particles Produced by a Single Recombinant Baculovirus Elicit Virus-Specific Immune Responses in Mice

Viruses, 2023
Porcine deltacoronavirus (PDCoV) causes diarrhea and vomiting in neonatal piglets worldwide and has the potential for cross-species transmission. Therefore, virus-like particles (VLPs) are promising vaccine candidates because of their safety and strong ...
Yangkun Liu, Xueying Han, Yaqi Qiao, Tiejun Wang, Lunguang Yao   +4 more
doaj   +1 more source

Emergence of a Highly Virulent Porcine Epidemic Diarrhea Virus (PEDV) G2c Subtype in China: Isolation, Genetic and Pathogenic Characterization, and Cross‐Neutralizing Antibody Response

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine epidemic diarrhea virus (PEDV), an enteropathogenic coronavirus causing high mortality in neonatal piglets, continues to threaten global swine industries. Frequent mutations in the spike (S) protein of PEDV, particularly in emerging variants, have substantially compromised commercial vaccine efficacy.
Yang-Yang Li, Chuan-Hao Fan, Hai-Xia Li, Hui-Qiang Zhen, Ye-Qing Zhu, Shouyu Wang, Bin Wang, Yao-Wei Huang, Linzhu Ren   +8 more
wiley   +1 more source

Correction to "Co-Infection of Porcine Epidemic Diarrhoea Virus and Porcine Deltacoronavirus Enhances the Disease Severity in Piglets". [PDF]

Transbound Emerg Dis
Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
europepmc   +2 more sources

Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Viral diseases are a major threat to human and animal health, as illustrated by recent pandemics like COVID‐19 and African swine fever (ASF). Timely, accurate detection of viral infections is critical for effective disease control. Among diverse diagnostic techniques, lateral flow immunoassay (LFIA) has become a widely used on‐site testing tool, owing ...
Quanyu Ren, Yan Wang, Haoyuan Ma, Jialiang Xie, Jianyou Jin, Rumeng Tian, Hao Yu, Xu Gao, Nanhua Chen   +8 more
wiley   +1 more source

Identification of novel serological agents for porcine deltacoronavirus infection based on the immunogenic accessory protein NS6

Animal Diseases
Porcine deltacoronavirus (PDCoV) is a swine enteropathogenic CoV that causes severe vomiting, diarrhea and dehydration in suckling piglets, leading to economic losses in the swine industry.
Yali Li, Fangshu Shi, Lingxiang Cao, Qiankun Zheng, Yaoyu Feng, Bin Wang, Yaowei Huang   +6 more
doaj   +1 more source

Co-infection of porcine deltacoronavirus and porcine epidemic diarrhea virus induces early TRAF6-mediated NF-κB and IRF7 signaling pathways through TLRs

Scientific Reports, 2022
Porcine deltacoronavirus (PDCoV) and porcine epidemic diarrhea virus (PEDV) infect the small intestine and cause swine enteric coronavirus disease. The mucosal innate immune system is the first line of defense against viral infection.
Kepalee Saeng-chuto, Adthakorn Madapong, Kampon Kaeoket, Pablo Enrique Piñeyro, Angkana Tantituvanont, Dachrit Nilubol   +5 more
doaj   +1 more source