Results 71 to 80 of about 112,162 (149)

Ultrasensitive Detection of Porcine Epidemic Diarrhea Virus Infections Using Multivalent DNA Nanostructure‐Enabled Lateral Flow Assay

Advanced Healthcare Materials, Volume 15, Issue 26, 10 July 2026.
A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao, Akhila Naru, Dhanush Gandavadi, Mengxi Zheng, Saraswathi Lanka, Hyeongjun Cho, Chau Nguyen Minh Hoang, Jianqiang Zhang, Ying Fang, Xing Wang   +9 more
wiley   +1 more source

Accurate detection of porcine deltacoronavirus infection and the importance of antibody stability in diagnostic specimens

, 2022
Porcine deltacoronavirus (PDCoV) is an enveloped, singled-stranded, positive-sense RNA virus that belongs to the family Coronaviridae, subfamily Coronavirinae and genus Deltacoronavirus.
Yen, Lu
core   +2 more sources

Identification of novel serological agents for porcine deltacoronavirus infection based on the immunogenic accessory protein NS6

Animal Diseases
Porcine deltacoronavirus (PDCoV) is a swine enteropathogenic CoV that causes severe vomiting, diarrhea and dehydration in suckling piglets, leading to economic losses in the swine industry.
Yali Li, Fangshu Shi, Lingxiang Cao, Qiankun Zheng, Yaoyu Feng, Bin Wang, Yaowei Huang   +6 more
doaj   +1 more source

Co-infection of porcine deltacoronavirus and porcine epidemic diarrhea virus induces early TRAF6-mediated NF-κB and IRF7 signaling pathways through TLRs

Scientific Reports, 2022
Porcine deltacoronavirus (PDCoV) and porcine epidemic diarrhea virus (PEDV) infect the small intestine and cause swine enteric coronavirus disease. The mucosal innate immune system is the first line of defense against viral infection.
Kepalee Saeng-chuto, Adthakorn Madapong, Kampon Kaeoket, Pablo Enrique Piñeyro, Angkana Tantituvanont, Dachrit Nilubol   +5 more
doaj   +1 more source

Genetic Diversity, Recombination, and Pathogenicity of Porcine Epidemic Diarrhea Virus Strains Circulating in China During 2023–2024

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine epidemic diarrhea virus (PEDV) is an enteric alphacoronavirus that causes severe diarrhea and high mortality in neonatal piglets, posing a persistent threat to the global swine industry. Despite extensive vaccination, PEDV continues to circulate in China, underscoring the need for updated molecular epidemiological surveillance.
Yunlei Cao, Ahui Cui, Xin Chen, Yang Cheng, Rongfeng Tang, Hui Zeng, Yuchen Li, Qian Yang, Linzhu Ren   +8 more
wiley   +1 more source

Preparation of a Single-Chain Antibody against Nucleocapsid Protein of Porcine Deltacoronavirus by Phage Display Technology

, 2022
Porcine deltacoronavirus (PDCoV) mainly causes severe diarrhea and intestinal pathological damage in piglets and poses a serious threat to pig farms. Currently, no effective reagents or vaccines are available to control PDCoV infection.
Haojie Ren, Yixuan Zhang, Yue Song, Lu Xia, Yixin Yuan, Quan Zeng, Zhanyong Wei   +6 more
core   +1 more source

Discovery of Cetaben as a Novel Antiviral Agent Against Porcine Epidemic Diarrhea Virus From a Cholesterol‐Lowering Compound Library

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The devastating impact of porcine epidemic diarrhea virus (PEDV) on the global swine industry underscores an urgent need for effective antiviral therapies. Drug repurposing presents a promising strategy to accelerate the development of such treatments.
Yaqin Li, Panpan Qin, Kaiqi Zhang, Ningning Ma, Tianliang Wang, Zilu Chen, Yixin Yuan, Dongliang Li, Linyang Yu, Wentao Li, Wenjuan Du, Yongtao Li, Jianchao Wei   +12 more
wiley   +1 more source

Development of a High‐Resolution Melting (HRM)‐Based Multiplex Real‐Time PCR Assay of PEDV, TGEV, PoRV, PDCoV, PRV, and PRRSV

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Six key viral pathogens—porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), porcine rotavirus (PoRV), porcine deltacoronavirus (PDCoV), pseudorabies virus (PRV), and porcine reproductive and respiratory syndrome virus (PRRSV)—inflict substantial economic losses on the global swine industry.
Fangshan Wang, Jing Ren, Yawen Wang, Chen Yuan, Tairan Sun, Jinhai Huang, Qinye Song, Nan-hua Chen   +7 more
wiley   +1 more source

Cross‐species transmission of deltacoronavirus and the origin of porcine deltacoronavirus

Evolutionary Applications, 2020
Deltacoronavirus is the last identified Coronaviridae subfamily genus. Differing from other coronavirus (CoV) genera, which mainly infect birds or mammals, deltacoronaviruses (δ‐CoVs) reportedly infect both animal types.
Xu Ye, Yingjin Chen, Xinyu Zhu, Jiahui Guo, Da Xie, Zhenzhen Hou, Shangen Xu, Junwei Zhou, Liurong Fang, Dang Wang, Shaobo Xiao   +10 more
doaj   +1 more source

The N-glycosylation at positions 652 and 661 of viral spike protein negatively modulates porcine deltacoronavirus entry

Frontiers in Veterinary Science
N-glycosylation is a highly conserved glycan modification that plays crucial roles in various physiological processes, including protein folding, trafficking, and signal transduction.
Hai-Ming Wang, Yang-Yang Qiao, Yong-Gang Liu, Bing-Yan Cai, Yue-Lin Yang, Hui Lu, Yan-Dong Tang, Yan-Dong Tang   +7 more
doaj   +1 more source