Results 61 to 70 of about 112,162 (149)

Utility Evaluation of Porcine Enteroids as PDCoV Infection Model in vitro

Frontiers in Microbiology, 2020
Porcine deltacoronavirus (PDCoV) is a novel emerging enteric coronavirus found in pigs. Intestinal enteroids, which partially recreate the structure and function of intestinal villi-crypts, have many physiological similarities to the intestinal tissues ...
Hao Luo, Jingyou Zheng, Yunlu Chen, Tingjun Wang, Zhenning Zhang, Ying Shan, Jidong Xu, Min Yue, Weihuan Fang, Xiaoliang Li   +9 more
doaj   +1 more source

Susceptibility of Cell Lines from Different Species to Porcine Deltacoronavirus. [PDF]

Viruses
Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus that causes severe diarrhea in piglets, leading to extensive economic losses in the global swine industry.
Jiang H, Lu B, Chu Y, Ma M, Zhang N, Xu Y, Chen Y, Xiao Q, Wang T, Peng Q.   +9 more
europepmc   +2 more sources

Development and application of a low-priced duplex quantitative PCR assay based on SYBR Green I for the simultaneous detection of porcine deltacoronavirus and porcine sapelovirus

Veterinární Medicína, 2023
Porcine deltacoronavirus (PDCoV) and porcine sapelovirus (PSV) are two viruses that can cause diarrhoea in pigs and bring great economic loss to the pig industry.
SJ Lu, MY Ma, XG Yan, FJ Zhao, WY Hu, QW Ding, HJ Ren, YQ Xiang, LL Zheng   +8 more
doaj   +1 more source

Complete Genome Characterization of Novel Chinese Porcine Deltacoronavirus Strain SD

, 2017
A porcine deltacoronavirus (PDCoV) was isolated and identified from feces of diarrheic piglets in Shandong Province of the Chinese mainland, and the complete genome of the Chinese PDCoV strain, SD, was sequenced and analyzed to further characterize PDCoV
Rui Chen, Qinghong Xue, Xing Zhang, Ziqi Zhang, Zhigang Zhang, Can Liu   +5 more
core   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Development of a nanobody-based competitive enzyme-linked immunosorbent assay for the sensitive detection of antibodies against porcine deltacoronavirus

Journal of Clinical Microbiology
Porcine deltacoronavirus (PDCoV) is an emerging porcine enteric coronavirus causing significant economic losses to the pig farming industry globally.
Ruiming Yu, Liping Zhang, Yingjie Bai, Peng Zhou, Jun Yang, Dongsheng Wang, Liyang Wei, Zhongwang Zhang, Chenghua Yan, Yonglu Wang, Huichen Guo, Li Pan, Ligang Yuan, Xinsheng Liu   +13 more
doaj   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Animal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Porcine Deltacoronavirus Engages the Transmissible Gastroenteritis Virus Functional Receptor Porcine Aminopeptidase N for Infectious Cellular Entry

, 2018
Identification of cellular receptors used by coronavirus (CoV) entry into the host cells is critical to an understanding of pathogenesis and to development of intervention strategies.
Bin Wang, Yan Liu, Xi-Mei Lei, Wen-Ting Luo, Yong-Le Yang, Jiyong Zhou, Pan Qin, Ling-Dong Xu, Qi-Zhang Liang, Chun-Miao Ji, Yao-Wei Huang, Pengwei Zhao   +11 more
core   +1 more source

GSDMD and GSDME exhibit distinct roles in enteric coronavirus PDCoV-induced pyroptosis and inflammatory responses

Journal of Virology
Porcine deltacoronavirus (PDCoV), an emerging enteric coronavirus with zoonotic potential, typically causes intestinal villous epithelial cell damage with inflammation.
Chenyu Li, Yuting Shi, Chunying Xie, Kaiqi Duan, Tong Ding, Xiangfei Xu, Liurong Fang, Yanrong Zhou, Shaobo Xiao   +8 more
doaj   +1 more source

Identification of a Novel Linear B-Cell Epitope on the Nucleocapsid Protein of Porcine Deltacoronavirus

, 2020
Porcine deltacoronavirus (PDCoV), first identified in 2012, is a swine enteropathogen now found in many countries. The nucleocapsid (N) protein, a core component of PDCoV, is essential for virus replication and is a significant candidate in the ...
Xintian Wen, Rui Chen, Xiaoping Ma, Xiaobo Huang, Jingfei Hu, Rui Wu, Qin Zhao, Sanjie Cao, Jiayu Fu, Huan Qu, Yujia Zhao, Yiping Wen   +11 more
core   +1 more source