Results 71 to 80 of about 18,401 (261)

Comparison of Vaccination Regimens on Immune Responses Using PED Replicon Vaccine: A Field Trial in PED-Negative and PED-Positive Thai Swine Farms

Animals
Porcine epidemic diarrhea virus (PEDV) is an economically important pathogen of swine, causing severe diarrhea in neonates with high morbidity and mortality.
Chaitawat Sirisereewan, Thanh Che Nguyen, Nanthiya Iampraphat, Hongyao Lin, Leonardo Ellerma, Pisit Sirithanyakul, Roongtham Kedkovid, Roongroje Thanawongnuwech   +7 more
doaj   +1 more source

Akkermansia muciniphila enhances chicken resistance to infectious bronchitis virus by boosting GABA synthesis and suppressing the NF‐κB inflammatory pathway

iMetaOmics, Volume 3, Issue 1, March 2026.
Infectious bronchitis virus (IBV) represents a major threat to poultry production, with current control strategies offering limited protection. In this study, we demonstrate gut microbiome is a critical determinant of IBV resistance using fecal microbiota transplantation.
Ouyang Peng, Yufang Liu, Xuanci Wang, Yihui Huang, Yiqin Yang, Qixiang Kang, Rui Geng, Guangli Hu, Aiping Lv, Fangyu Hu, Yongbo Xia, Xin Luo, Jiamin Liao, Yihong He, Zhanpeng Kuang, Yunping Du, Yun Zhang, Chunyi Xue, Zongxi Han, Wen‐Jun Li, Lei Dong, Hao Zhang, Yongchang Cao   +22 more
wiley   +1 more source

Prediction of Intrinsic Disorder in MERS-CoV/HCoV-EMC Supports a High Oral-Fecal Transmission [PDF]

, 2013
A novel coronavirus, MERS-CoV (NCoV, HCoV-EMC/2012), originating from the Middle-East, has been discovered. Incoming data reveal that the virus is highly virulent to humans.
Dunker, A. Keith, Goh, Gerard Kian-Meng, Uversky, Vladmir   +2 more
core   +1 more source

Development of Effective PEDV Vaccine Candidates Based on Viral Culture and Protease Activity

Vaccines, 2023
Porcine epidemic diarrhea (PED) is a highly contagious disease that has been reported annually in several Asian countries, causing significant economic losses to the swine livestock industry. Although vaccines against the porcine epidemic diarrhea virus (
Dae-Min Kim, Sung-Hyun Moon, Seung-Chai Kim, Ho-Seong Cho, Dongseob Tark   +4 more
doaj   +1 more source

Management and Biosecurity Practices of Pig Farms in Nepal

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
1) Biosecurity adoption level of pig farmers in Nepal is low. 2) The pig farms are highly vulnerable to infectious diseases like African swine fever. 3) Governments of Nepal should take immediate actions focusing on capacity building of pig farmers, information dissemination and adoption of biosecurity practices.
Sachin Shrestha, Alok Dhakal, Ramjee Ghimire, Min Bahadur Oli, Rakesh Kumar Yadav, Nishant Shah   +5 more
wiley   +1 more source

Genetic characterization and phylogenetic analysis of porcine epidemic diarrhea virus in Guangdong, China, between 2018 and 2019.

PLoS ONE, 2021
Porcine epidemic diarrhea virus (PEDV), a leading cause of piglet diarrhea outbreaks, poses a significant danger to the swine industry. The aim of this study was to investigate the epidemic characteristics of PEDV that was circulating in Guangdong ...
Feng Wen, Jing Yang, Anqi Li, Zhonggui Gong, Lulu Yang, Qing Cheng, Congying Wang, Mengmeng Zhao, Sheng Yuan, Yao Chen, Saeed El-Ashram, Yong Li, Hai Yu, Jinyue Guo, Shujian Huang   +14 more
doaj   +1 more source

Prevention and Control of Swine Enteric Coronaviruses in China: A Review of Vaccine Development and Application

Vaccines, 2023
Swine enteric coronaviruses (SECs) cause significant economic losses to the pig industry in China. Although many commercialized vaccines against transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhea virus (PEDV) are available, viruses ...
Fanzhi Kong, Huilin Jia, Qi Xiao, Liurong Fang, Qiuhong Wang   +4 more
doaj   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, Volume 15, Issue 8, 23 February 2026.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Trypsin-induced hemagglutination activity of porcine epidemic diarrhea virus [PDF]

Archives of Virology, 2010
The hemagglutination (HA) activity of porcine epidemic diarrhea virus (PEDV) was investigated. Two cell-adapted strains of PEDV (KPEDV-9 and SM98LVec) were subjected to HA test against erythrocytes of various origin. Both strains showed HA activity with rabbit erythrocytes only after treatment with trypsin or neuraminidase.
Park, Jung-Eun, Cruz, Deu John M., Shin, Hyun-Jin   +2 more
openaire   +2 more sources

Krisanaklan Reduces Intestinal Anion and Fluid Secretion Through Inhibition of Na+/K+‐ATPase and K+ Channel Activity

Annals of the New York Academy of Sciences, Volume 1556, Issue 1, February 2026.
Krisanaklan reduces CFTR‐dependent intestinal chloride and fluid secretion by inhibiting the Na+,K+‐ATPase and K+ channels in epithelial cells. Consequently, this natural, plant‐derived product may limit secretory diarrhea caused by a diverse array of microbial pathogens. However, by dissipating the transmembrane Na+ gradient, Krisanaklan also inhibits
Tessa A. Groeneweg, Erdene Baigal, Anny Leung, Gert‐Jan Kremers, Marcel J. C. Bijvelds   +4 more
wiley   +1 more source