Results 61 to 70 of about 7,279 (124)

No Evidence of Viral Transmission following Long‐Term Implantation of Agarose Encapsulated Porcine Islets in Diabetic Dogs

Journal of Diabetes Research, Volume 2014, Issue 1, 2014., 2014
We have previously described the use of a double coated agarose‐agarose porcine islet macrobead for the treatment of type I diabetes mellitus. In the current study, the long‐term viral safety of macrobead implantation into pancreatectomized diabetic dogs treated with pravastatin (n = 3) was assessed while 2 dogs served as nonimplanted controls.
Lawrence S. Gazda, Horatiu V. Vinerean, Melissa A. Laramore, Richard D. Hall, Joseph W. Carraway, Barry H. Smith, Åke Lernmark   +6 more
wiley   +1 more source

Limited availability of methods for the detection of xenotransplantation‐relevant viruses in veterinary laboratories

Xenotransplantation, Volume 31, Issue 3, May/June 2024.
Abstract Background The German Xenotransplantation Consortium is in the process to prepare a clinical trial application (CTA) on xenotransplantation of genetically modified pig hearts. In the CTA documents to the central and national regulatory authorities, that is, the European Medicines Agency (EMA) and the Paul Ehrlich Institute (PEI), respectively,
Joachim Denner
wiley   +1 more source

Metavirome Analysis Reveals a High Prevalence of Porcine Hemagglutination Encephalomyelitis Virus in Clinically Healthy Pigs in China

Pathogens, 2023
Six swine coronaviruses (SCoVs), which include porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), porcine hemagglutination encephalomyelitis virus (PHEV), porcine respiratory coronavirus (PRCV), swine acute diarrhea syndrome coronavirus (SADS-CoV), and porcine delta coronavirus (PDCoV), have been reported as infecting ...
Weiyao Sun, Zhibin Shi, Pengfei Wang, Bingbing Zhao, Jiaqi Li, Xinyu Wei, Lili Wei, Jingfei Wang   +7 more
openaire   +3 more sources

Cross‐Correlation between Biosecurity Measures and the Detection of Viral and Bacterial Agents on German Farms with Respiratory Disease

Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
Effective porcine health management relies majorly on diagnostic tests, vaccination, treatment strategies, and a proper biosecurity management plan. However, understanding the link between circulating microbes and biosecurity measures on a pig farm is not evident.
Julia Stadler, Kathrin Lillie-Jaschniski, Sophia Zwickl, Susanne Zoels, Sebastiaan Theuns, Mathias Ritzmann, Nick Vereecke, Jordi Casal   +7 more
wiley   +1 more source

Porcine Hemagglutinating Encephalomyelitis Virus

, 1983
This chapter provides an overview of the classification, description, hosts, key developments, diagnostic techniques, and diagnostic reagents for porcine hemagglutinating encephalomyelitis virus. Porcine hemagglutinating encephalomyelitis virus belongs to the family Coronaviridae; genus Coronavirus; and species Porcine hemagglutinating ...
openaire   +1 more source

Cultivation techniques for animal coronaviruses: Emphasis on feline infectious peritonitis virus, canine coronavirus, transmissible gastroenteritis virus, and porcine hemagglutinating encephalomyelitis virus [PDF]

Journal of Tissue Culture Methods, 1988
Techniques are described for the growth and characterization of some mammalian coronaviruses. Because of the fastidious nature of their growth requirements, most will replicate only in cells derived from the natural host or a closely related species. Fetal cat cells are used to grow FIPV, and porcine cells are used to grow TGEV and HEV.
Woods, Roger D., Wesley, Ronald D.
openaire   +2 more sources

Development of Reverse Transcriptase PCR and Nested PCR to Detect Porcine Hemagglutinating Encephalomyelitis Virus

Journal of Veterinary Medical Science, 2004
Porcine hemagglutinating encephalomyelitis virus (HEV) causes encephalomyelitis, or vomiting and wasting disease, in suckling piglets. The mortality rate for piglets under 3 weeks old is 100%, but they are usually protected by maternal antibodies. Recently, the risk of an HEV outbreak has increased in the pig industry, because of widely using specific ...
Yoshiko, Sekiguchi, Junsuke, Shirai, Takahide, Taniguchi, Eiichi, Honda   +3 more
openaire   +3 more sources

In vitro inhibition of porcine hemagglutinating encephalomyelitis virus replication with siRNAs targeting the spike glycoprotein and replicase polyprotein genes. [PDF]

Intervirology, 2012
<i>Objective:</i> The specific effect of RNA interference on the replication of porcine hemagglutinating encephalomyelitis virus (PHE-CoV) was explored. <i>Methods:</i> Four species of small interfering RNA (siRNA), targeting different regions of the PHE-CoV spike glycoprotein and replicase polyprotein genes, were prepared by in
Lan Y, Lu H, Zhao K, He W, Chen K, Wang G, Song D, Gao F.   +7 more
europepmc   +4 more sources

IDENTIFICATION AND GENETIC CHARACTERIZATION OF PORCINE HEMAGGLUTINATING ENCEPHALOMYELITIS VIRUS IN RUSSIA

PIG-BREEDING
Swine coronaviruses (SCoVs), comprising members of the genera Alphacoronavirus, Betacoronavirus, and Deltacoronavirus, include several important pathogens responsible for economically significant diseases in pigs. Among them, porcine hemagglutinating encephalomyelitis virus (PHEV), a betacoronavirus, represents a potential threat to swine health ...
T.D. MUSAEVA, E.B. SHAITAROVA, N.D. YOLSHIN, D.M. DANILENKO, E.V. STOLBOV, V.V. PRUGLO, D.A. LIOZNOV, A.V. KOMISSAROV   +7 more
openaire   +1 more source

Transcriptome Analysis in Air–Liquid Interface Porcine Respiratory Epithelial Cell Cultures Reveals That the Betacoronavirus Porcine Encephalomyelitis Hemagglutinating Virus Induces a Robust Interferon Response to Infection

Viruses
Porcine hemagglutinating encephalomyelitis virus (PHEV) replicates in the upper respiratory tract and tonsils of pigs. Using an air–liquid interface porcine respiratory epithelial cells (ALI-PRECs) culture system, we demonstrated that PHEV disrupts ...
Kaitlyn M. Sarlo Davila, Rahul K. Nelli, Juan C. Mora-Díaz, Yongming Sang, Laura C. Miller, Luis G. Giménez-Lirola   +5 more
doaj   +1 more source