A Selected Lactobacillus rhamnosus Strain Promotes EGFR-Independent Akt Activation in an Enterotoxigenic Escherichia coli K88-Infected IPEC-J2 Cell Model. [PDF]
Enterotoxigenic Escherichia coli (ETEC) are important intestinal pathogens that cause diarrhea in humans and animals. Although probiotic bacteria may protect against ETEC-induced enteric infections, the underlying mechanisms are unknown.
Wei Zhang +5 more
doaj +1 more source
Phytic acid protects porcine intestinal epithelial cells from deoxynivalenol (DON) cytotoxicity [PDF]
The purpose of this study was to evaluate the effects of phytic acid (IP(6)) as a possible inhibitor of cellular damage induced by toxic substances such as mycotoxins on a porcine intestinal epithelial cell line (IPEC-1). We first observed that a dose of 5 mM phytic acid decreases cell viability and transepithelial electrical resistance (TEER) of cell ...
Pacheco, Graziela Drociunas +4 more
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Physiological Concentration of Exogenous Lactate Reduces Antimycin A Triggered Oxidative Stress in Intestinal Epithelial Cell Line IPEC-1 and IPEC-J2 In Vitro. [PDF]
Weaning triggers an adaptation of the gut function including luminal lactate generation by lactobacilli, depending on gastrointestinal site. We hypothesized that both lactobacilli and lactate influence porcine intestinal epithelial cells.
Stefan Kahlert +11 more
doaj +1 more source
Cell lineage identification and stem cell culture in a porcine model for the study of intestinal epithelial regeneration. [PDF]
Significant advances in intestinal stem cell biology have been made in murine models; however, anatomical and physiological differences between mice and humans limit mice as a translational model for stem cell based research.
Liara M Gonzalez +4 more
doaj +1 more source
Lactadherin orthologs inhibit migration of human, porcine and murine intestinal epithelial cells [PDF]
AbstractLactadherin was originally described due to its appearance in milk, but is abundantly expressed especially by professional and nonprofessional phagocytes. The proteins has been shown to have a multitude of bioactive effects, including inhibition of inflammatory phospholipases, induction of effero‐ and phagocytosis, prevent rotavirus induced ...
Steffen Nyegaard +2 more
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In vitro study of chlorine dioxide on porcine intestinal epithelial cell gene markers [PDF]
Background Chlorine dioxide (ClO 2 ) is an inorganic, potent biocide and is available in highly purified aqueous solution. It can be administered as an oral antiseptic in this form.
Orsolya Palócz +4 more
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Beta-toxin (CPB) is the essential virulence factor of C. perfringens type C causing necrotizing enteritis (NE) in different hosts. Using a pig infection model, we showed that CPB targets small intestinal endothelial cells.
Simone Roos +6 more
doaj +1 more source
Background: Polyamines have been demonstrated to be beneficial to porcine intestinal development. Our previous study showed that putrescine mitigates intestinal atrophy in weanling piglets and suppresses inflammatory response in porcine intestinal ...
Zi-xi Wei +4 more
doaj +1 more source
Morphogenesis of Porcine Rotavirus in Porcine Kidney Cell Cultures and Intestinal Epithelial Cells
The morphogenesis of porcine rotavirus was similar in vitro in porcine kidney (PK) cell cultures and in vivo in porcine epithelial cells as examined by electron microscopy. Infected cells contained cytoplasmic, non-membrane-bound viroplasm and accumulations of virus particles within cisternae of the rough endoplasmic reticulum (RER).
L J, Saif, K W, Theil, E H, Bohl
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Lactobacillus casei (L. casei), a normal resident of the gastrointestinal tract of mammals, has been extensively studied over the past few decades for its probiotic properties in clinical and animal models.
Yongfei Bai +6 more
doaj +1 more source

