Results 91 to 100 of about 2,648 (172)

Genome‐wide siRNA library screening identifies human host factors that influence the replication of the highly pathogenic H5N1 influenza virus

mLife, Volume 4, Issue 1, Page 55-69, February 2025.
Abstract The global dissemination of H5 avian influenza viruses represents a significant threat to both human and animal health. In this study, we conducted a genome‐wide siRNA library screening against the highly pathogenic H5N1 influenza virus, leading us to the identification of 457 cellular cofactors (441 proviral factors and 16 antiviral factors ...
Guangwen Wang, Li Jiang, Jinliang Wang, Qibing Li, Jie Zhang, Fandi Kong, Ya Yan, Yuqin Wang, Guohua Deng, Jianzhong Shi, Guobin Tian, Xianying Zeng, Liling Liu, Zhigao Bu, Hualan Chen, Chengjun Li   +15 more
wiley   +1 more source

PAX6 isoforms, along with reprogramming factors, differentially regulate the induction of cornea-specific genes [PDF]

, 2016
PAX6 is the key transcription factor involved in eye development in humans, but the differential functions of the two PAX6 isoforms, isoform-a and isoform-b, are largely unknown.
Hayashi, Ryuhei, Kawasaki, Satoshi, Nakai, Kenta, Nishida, Kohji, Park, Sung-Joon, Quantock, Andrew J, Saito-Adachi, Mihoko, Sasamoto, Yuzuru, Suzuki, Yutaka, Tsujikawa, Motokazu   +9 more
core   +2 more sources

CaribVET, le réseau caribéen de santé animale [PDF]

, 2011
Le Réseau caribéen de santé animale CaribVET a été créé en l'an 2000 afin de contribuer au renforcement et à l'harmonisation de la surveillance et du contrôle des maladies animales transfrontalières pour améliorer la situation sanitaire et la ...
Bournez, Laure, Gongora, Victor, Kalloo, Margaret, Lefrançois, Thierry, Petit Sinturel, Marion, Pradel, Jennifer, Shaw, John, Vachiery, Nathalie   +7 more
core  

Lentiviral vectors can be used for full-length dystrophin gene therapy [PDF]

, 2017
Duchenne Muscular Dystrophy (DMD) is caused by a lack of dystrophin expression in patient muscle fibres. Current DMD gene therapy strategies rely on the expression of internally deleted forms of dystrophin, missing important functional domains.
Asgarian, Z, Counsell, JR, Danos, O, Ferrer, V, Howe, SJ, Meng, J, Morgan, JE, Muntoni, F, Thrasher, AJ, Vink, CA, Waddington, SN   +10 more
core   +2 more sources

Neuropeptide VF neurons promote sleep via the serotonergic raphe [PDF]

, 2020
Although several sleep-regulating neuronal populations have been identified, little is known about how they interact with each other to control sleep/wake states.
Andreev, Andrey, Cammidge, Tasha, Hong, Young, Hurley, Hannah, Lee, Daniel A., Oikonomou, Grigorios, Prober, David A.   +6 more
core  

Identification of Novel Rosavirus Species That Infects Diverse Rodent Species and Causes Multisystemic Dissemination in Mouse Model [PDF]

, 2016
published_or_final_versio
Chan, BC, Chan, KH, Chen, Z, Fan, YY, Lam, SF, Lau, SKP, Li, KSM, Woo, PCY, Yip, CY, Yuen, KY, Yuen, MC, Zhang, HJ, Zhang, J   +12 more
core   +1 more source

Steric regulation of tandem calponin homology domain actin-binding affinity. [PDF]

, 2019
Tandem calponin homology (CH1-CH2) domains are common actin-binding domains in proteins that interact with and organize the actin cytoskeleton. Despite regions of high sequence similarity, CH1-CH2 domains can have remarkably different actin-binding ...
Bausch, Andreas, Belardi, Brian, Fletcher, Daniel A, Harris, Andrew R, Jreij, Pamela, Shams, Hengameh, Wei, Kathy   +6 more
core   +1 more source

A visual reporter system for transgene screening and monitoring genome editing in tomato

Vegetable Research
The stable expression of integrated transgenes remains a major restriction in plant transformation, as different vector backbones and host contexts often lead to variable or silenced expression.
Ningkai An, Jinbo Wei, Shiliang Chen, Xiaoyue Yang, Kemeng Wu, Xinjie Zhou, Jie Wang, Shasha Wu, Shurong Wu, Chenyi Liu, Yueyue Fu, Jinyu Zhang, Weizhen Yi, Huijun Zhu, Chao Sun, Shuang Wu   +15 more
doaj   +1 more source

Human enterovirus 71 and hand, foot and mouth disease [PDF]

, 2010
Hand, foot and mouth disease (HFMD) is generally a benign febrile exanthematous childhood disease caused by human enteroviruses. The route of transmission is postulated to be faeco-oral in developing areas but attributed more to respiratory droplet in ...
Lau, SKP, Wong, SSY, Yip, CCY, Yuen, KY
core   +1 more source

In vivo measurement of afferent activity with axon-specific calcium imaging. [PDF]

, 2018
In vivo calcium imaging from axons provides direct interrogation of afferent neural activity, informing the neural representations that a local circuit receives.
Broussard, Gerard Joey, Fridman, Marina, Ji, Na, Liang, Yajie, Meng, Guanghan, Petreanu, Leopoldo, Tian, Lin, Unger, Elizabeth K, Xiao, Xian   +8 more
core