Results 241 to 250 of about 759,323 (315)

Membrane-Spanning Nanopores Formed from Nucleic Acids. [PDF]

Chem Rev
Li Y, Karrasch T, Keyser UF, Göpfrich K.   +3 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Effect of Steel Slag Content on the Performance and Hydration Mechanism of Phosphogypsum-Steel Slag-Fly Ash All-Solid-Waste Binders. [PDF]

Materials (Basel)
Liu D, Wang Y, Zhang B, Ma Y.
europepmc   +1 more source

Lignin-Derived Hierarchical Porous Solid Base for Efficient Glucose Isomerization via In Situ Active Site Generation. [PDF]

Materials (Basel)
Yang M, Xu J, Song P, Li A, Zou M, Zhou S.   +5 more
europepmc   +1 more source

Preparation of Expanded Graphite/Paraffin-Based Composite Phase Change Materials (PCMs) via Low-Temperature In Situ Synchronous Expansion. [PDF]

ACS Omega
Yang H, Zhang Y, Cui B, Li W, Zhao Q.
europepmc   +1 more source

Sorption of Antibiotics in Sewage Sludge: Distribution Coefficients, Sludge Characteristics, and Implications for Environmental Fate. [PDF]

J Xenobiot
Shin W, Kim PG, Oak MH.
europepmc   +1 more source

Antifreeze Protein for Freeze-Thaw Durability Enhancement of Cement Mortar: Effects and Action Analysis. [PDF]

Materials (Basel)
Zhang Q, Gong J, Gong M.
europepmc   +1 more source