Results 91 to 100 of about 7,489,349 (254)

Tests for Sandstone Strength and Failure Model under Water Pressure

open access: yes工程科学与技术, 2015
:The strength and failure forms under high water pressure are important for deep buried and high water pressure tunnel and under groud mining. The conventional uniaxial experiment and the compression tests under different water pressure were carried out ...
CHEN Ying, MA Dong-tao, HE De-wei
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Two-dimensional consolidation of unsaturated–saturated soil foundations under plane strain conditions based on an interfacial flow contact model

open access: yesSoils and Foundations
A two-dimensional consolidation model for unsaturated–saturated soils under plane strain conditions is developed based on Fredlund’s and Terzaghi’s consolidation theories for unsaturated and saturated soils, respectively. Furthermore, an interfacial flow
Dansheng Yu   +7 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

A Method to Estimate Dynamic Pore Water Pressure Growth of Saturated Sand-Gravel Materials

open access: yesApplied Sciences
The liquefaction of saturated sand-gravel material samples from the Xinjiang valley were investigated under cyclic loading. A series of large-scale dynamic triaxial tests were used to determine the dynamic characteristics of the sand-gravel sample under ...
Jinyi Chen   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Pore structure features of reservoirs at late high water-cut stage, Lamadian Oilfield, Daqing, China

open access: yesPetroleum Exploration and Development, 2008
: Lamadian Oilfield has entered a high water-cut stage after long-term water flooding, and injected water circulates in high-permeability channels. Constant-rate and constant-pressure mercury injections were used to study the change in the physical ...
Yu-bao LIN   +3 more
doaj   +1 more source

Stability of saturated cohesionless soil layer due to water flowing from a broken underground pipeline

open access: yes, 2000
An experimental study was conducted to assess the effect of the increase in pore water pressure, caused by water flowing from an underground pipeline, on the stability of a saturated cohesionless soil layer.
AI-Karni,Awad A. S.
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Distribution of pore water pressure in an earthen dam considering unsaturated-saturated seepage analysis

open access: yesE3S Web of Conferences, 2016
The variation of pore water pressure in earthen dams plays an important role in maintaining its stability. The pore water pressure within the dam are altered by the external loading conditions like rapid drawdown of reservoir water, earthquake loading ...
Venkatesh Kumar, Karumanchi Siva Ram
doaj   +1 more source

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