Results 71 to 80 of about 7,489,349 (254)

Clathrate formation and dissociation in vapor/water/ice/hydrate systems in SBA-15, sol-gel and CPG porous media, as probed by NMR relaxation, novel protocol NMR cryoporometry, neutron scattering and ab initio quantum-mechanical molecular dynamics simulation [PDF]

, 2007
The Gibbs-Thomson effect modifies the pressure and temperature at which clathrates occur, hence altering the depth at which they occur in the seabed. Nuclear magnetic resonance (NMR) measurements as a function of temperature are being conducted for water/
Webber, J. Beau W., Anderson, Ross, Anderson, Ross A., Tohidi, Bahman, Strange, John H., Tohidi, Bahman; id_orcid, Webber, J. B. W.   +6 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Changes in excess pore water pressure in soft ground under multi-factor influences coupled with positive and negative pressure

Shuiwen dizhi gongcheng dizhi
Vacuum stacking joint pre-compression method is widely used to reinforce soft ground. During the preloading process, a coupled mechanism involving positive and negative pore-water pressures develops within the soil, and the reinforcement performance is ...
Hongjun LIU, Feng CHEN, Chao YANG
doaj   +1 more source

Variation of Pore Water Pressure in Tailing Sand under Dynamic Loading

Shock and Vibration, 2018
Intense vibration affects the pore water pressure in a tailing dam, with the tendency to induce dam liquefaction. In this study, experiments were performed wherein model tailing dams were completely liquefied by sustained horizontal dynamic loading to ...
Jia-xu Jin, Hong-zhi Cui, Li Liang, Shi-wang Li, Ping-yi Zhang   +4 more
doaj   +1 more source

Three Dimensional Seepage Analyses in Mollasadra Dam after Its Impoundments

Journal of Applied Sciences and Environmental Management, 2011
Mollasadra dam is an earth fill dam with a clayey core and a height of 72 m from river bed, constructed on Kor River. pore water pressure in the dam was investigated following its construction and first and second impoundments.
GR Rakhshandehroo, M Vaghefi, ARH Zadeh
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Research on landslide displacement prediction method considering pore water pressure

Zhongguo dizhi zaihai yu fangzhi xuebao
Landslide displacement prediction is a critical component of disaster prevention and mitigation. Rainfall infiltration directly affects the distribution of pore water pressure within the landslide mass, and the dynamic variation of pore water pressure ...
Yu QIAN, Li WANG, Bao SHU, Hao XU, Bin CHEN, Tianyu GENG, Hanwen WU   +6 more
doaj   +1 more source

A Mechanistic Explanation of The Physical Properties of Undisturbed Loess, February;HR-126, 1968 [PDF]

, 1968
The relation between the properties and the water content of an undisturbed loess were investigated to provide insight into the mechanical behavior of the natural soil.

core  

Experimental Study on Determining Unsaturated Property of Soil [PDF]

, 1980
This paper deals with the experimental study of hydraulic properties of unsaturated soil. In treating unsaturated zone, a great deal more data are required than are required for the saturated zone, but these properties of soils must be known to apply the
Nishigaki, Makoto, Kono, Iichiro
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source