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Porphyria Cutanea Tarda

Archives of Dermatology, 1958
Introduction Porphyria is thought to be an "inborn error of metabolism" (Garrod, 1923), i. e., of pyrrole metabolism. Quite a number of classifications of porphyria have been described, but among them the best known are those of Waldenstrom (1937) and of Schmid, Schwartz, and Watson (1953, 1954). In order to avoid any confusion the classifications of
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DIAZINON AND PORPHYRIA CUTANEA TARDA

Medical Journal of Australia, 1979
Cutaneous application of diazinon to rats over a period of 12 weeks gives rise to a condition biochemically indistinguishable from porphyria cutanea tarda. Faecal porphyrin levels are elevated with the appearance of isocoproporphyrin in the faeces. Oral administration of diazinon does not appear to cause any disturbance of porphyrin metabolism.
P, Bleakley, A W, Nichol, A G, Collins
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Porphyria cutanea tarda and pregnancy

American Journal of Obstetrics and Gynecology, 1983
Porphyria cutanea tarda (PCT) is an inborn error of metabolism. It is one of a family of six genetically distinct porphyrias and is characterized by a disorder of heme synthesis, resulting in the excess accumulation and excretion of uroporphyrins and coproporphyrins.
L V, Baxi   +3 more
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Causes of Porphyria Cutanea Tarda

Archives of Dermatology, 1977
To the Editor.— Porphyria cutanea tarda (PCT) is a disorder with multiple causes, and the liver appears to be the main target organ that regulates the breakdown metabolism of heme. Unfortunately, not all the proven causes are well known, and I was surprised at a recent meeting to hear a well-known expert on porphyrins give only a partial list of ...
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Porphyria cutanea tarda and sarcoidosis

Clinical and Experimental Dermatology, 1982
Summary A case of porphyria cutanea tarda and sarcoidosis involving the lungs and liver is described. This appears to he the second case showing such an association reported in the English literature. The relationship between the two conditions and their response to prednisolone is discussed.
R J, Mann, R R, Harman
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FAMILIAL PORPHYRIA CUTANEA TARDA *

Australasian Journal of Dermatology, 1985
SUMMARYThe results of erythrocyte uroporphyrinogen decarboxylase estimations of members of the family of a child with porphyria cutanea tarda are reported.
M, Rogers, V, Poulos
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Porphyria Cutanea Tarda and Pregnancy

Obstetrical & Gynecological Survey, 1996
Porphyria cutanea tarda is the most common disorder of porphyrin metabolism in Europe and North America. The disorder is characterized by specific cutaneous lesions, associated systemic findings, and excessive accumulation and excretion of uroporphyrin and coproporphyrins. Reports of this condition associated with pregnancy are scarce in the literature.
J R, Loret de Mola   +2 more
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Porphyria cutanea tarda and sarcoidosis

Journal of the American Academy of Dermatology, 1980
A 38-year-old black woman presented with a multisystem disease characterized by malaise, fever, sweats, and diffuse hyperpigmentation. Laboratory examinations showed anemia, elevated alkaline phosphatase, granulomas in the liver and bone marrow, and elevated porphyrins in the urine and feces, characteristic of porphyria cutanea tarda (PCT).
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Porphyria Cutanea Tarda and Estrogens

JAMA: The Journal of the American Medical Association, 1967
Porphyria cutanea tarda can be induced by a variety of compounds, including estrogens. Cutaneous manifestations of the disease are characterized chiefly by a light- and trauma-sensitive eruption of exposed areas. In two cases occurring secondary to estrogens, improvement followed estrogen withdrawal.
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Porphyria cutanea tarda in Ethiopia

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1981
The clinical, biochemical and histological features of 75 Ethiopians with porphyria cutanea tarda (PCT) are described. PCT in Ethiopia is definitely related to alcohol abuse and there is no clinical evidence for hereditary predisposition. Significant elevation of transaminases and bromsulphthalein retention, moderate to marked hepatic siderosis and ...
E, Tsega   +3 more
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