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Perkembangan Plasenta dan Pertumbuhan Janin pada Tikus Hamil yang Diinfeksi Porphyromonas Gingivalis Placental Development and Fetal Growth in Porphyromonas Gingivalis-Infected Pregnant Rats [PDF]

open access: yesInsisiva Dental Journal, 2014
Maternal Porphyromonasgingivalis infection on periodontal tissue can result in Porphyromonasgingivalis dissemination to umbillical cord. Porphyromonas gingivalis presumably gain access to the systemic circulation via local tissue inflammation, and may ...
Banun Kusumawardani   +2 more
doaj   +4 more sources

Colonization by Porphyromonas gingivalis in cervical squamous cell carcinomas promotes metastasis through FimA/CD151/ITGB1 signaling [PDF]

open access: yesJournal of Translational Medicine
Background Cervicovaginal microbiota dysbiosis has been implicated in the progression of cervical cancer. Recent studies have reported an increased abundance of Porphyromonas species in the vaginal microbiota of cervical cancer patients.
Xiuting Huang   +18 more
doaj   +2 more sources

A Pulmonary Abscess Caused by Porphyromonas gingivalis Infection: A Case Report and Literature Review [PDF]

open access: yesThe Clinical Respiratory Journal
Lung abscess is a common disease in respiratory medicine, which is a suppurative lesion caused by various pathogens, and microbiological examination is crucial for the treatment of lung abscess.
Xu Chen, Ling Wu, Ruoxi Wu, Jiajia Dong
doaj   +2 more sources

Porphyromonas gingivalis bacterium as a risk factor for Alzheimer’s disease! [PDF]

open access: yesNovel Research in Microbiology Journal, 2023
Alzheimer’s disease remains a significant socio-economic problem in modern medicine. This disease is a neurodegenerative one that is characterized by the plaque formation and neurofibrillary tangles, due to the accumulation of β-amyloid peptide in the ...
Andrei V. Kozlov   +4 more
doaj   +1 more source

Identification of Small-Molecule Inhibitors against Meso-2, 6-Diaminopimelate Dehydrogenase from Porphyromonas gingivalis [PDF]

open access: yes, 2015
Species-specific antimicrobial therapy has the potential to combat the increasing threat of antibiotic resistance and alteration of the human microbiome.
Chen, Weihau   +7 more
core   +14 more sources

Phylogenomic analysis of the Porphyromonas gingivalis - Porphyromonas gulae duo: approaches to the origin of periodontitis

open access: yesFrontiers in Microbiology, 2023
Porphyromonas gingivalis is an oral human pathogen associated with the onset and progression of periodontitis, a chronic immune-inflammatory disease characterized by the destruction of the teeth-supporting tissue. P.
Mauricio Morales-Olavarría   +8 more
doaj   +1 more source

Investigation of potential targets of Porphyromonas CRISPRs among the genomes of Porphyromonas species. [PDF]

open access: yesPLoS ONE, 2017
The oral bacterial species Porphyromonas gingivalis, a periodontal pathogen, has plastic genomes that may be driven by homologous recombination with exogenous deoxyribonucleic acid (DNA) that is incorporated by natural transformation and conjugation ...
Takayasu Watanabe   +4 more
doaj   +1 more source

Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine-gingipain inhibitor COR388. [PDF]

open access: yes, 2020
COR388, a small-molecule lysine-gingipain inhibitor, is currently being investigated in a Phase 2/3 clinical trial for Alzheimer's disease (AD) with exploratory endpoints in periodontal disease.
Arastu-Kapur, Shirin   +10 more
core   +1 more source

High Levels of Leptin and Adipsin Are Associated with Clinical Activity in Early Rheumatoid Arthritis Patients with Overweight and Periodontal Infection

open access: yesDiagnostics, 2023
Adipokines are associated with the pathogenesis of rheumatoid arthritis (RA) and are potential biomarkers of disease activity, periodontitis, and obesity.
Consuelo Romero-Sánchez   +8 more
doaj   +1 more source

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