Results 71 to 80 of about 8,412,464 (305)

Redefining the Surface Anatomy of Major Abdominal Structures in an Adult Population: A Computed Tomography Evaluation

Clinical Anatomy, EarlyView.
ABSTRACT Inconsistencies exist in anatomy and clinical reference texts regarding the vertebral levels of major abdominal structures. Accurate surface anatomy is essential for diagnostic interpretation and interventional procedures, yet little is known about how health status or pathology may influence the vertebral relationships of abdominal organs ...
Masroor Badshah, Muhammad Ibrahim, Khaled A. Elnahriry, Roger Soames   +3 more
wiley   +1 more source

Features of encephalopathy diagnosis in patients with portal hypertension syndrome

Gastroenterologìa, 2017
Background. Hepatic encephalopathy is a pathological change in the brain functions of non-inflammatory origin, which is manifested by a syndrome of secondary neurological and cognitive disorders caused by a set of deep metabolic disorders, as a result of
Yu.M. Stepanov, N.V. Chaliy, S.L. Меlanich   +2 more
doaj   +1 more source

Portal‐hypertensive gastropathy

Journal of Gastroenterology and Hepatology, 1998
ABSTRACTIn the present article we describe updated information concerning the clinical feature of portal‐hypertensive gastropathy (PHG), which is characterized by mucosal and submucosal vascular dilatation without inflammation. Although this lesion represents non‐variceal bleeding, there is a wide variation of its prevalence.
TOYONAGA, Atsushi, IWAO, Tadashi
openaire   +3 more sources

Hepatic microcirculation and mechanisms of portal hypertension.

, 2019
The liver microcirculatory milieu, mainly composed of liver sinusoidal endothelial cells (LSECs), hepatic stellate cells (HSCs) and hepatic macrophages, has an essential role in liver homeostasis, including in preserving hepatocyte function, regulating ...
Anabel Fernández-Iglesias, Fernández-Iglesias, Anabel, Gracia Sancho, Jorge Sergio, Jordi Gracia-Sancho, Giusi Marrone, Marrone, Giusi   +5 more
core   +1 more source

Prolonged fenfluramine use in open‐label studies of Dravet or Lennox–Gastaut syndromes: Long‐term safety, tolerability, patient global functioning, and considerations for interpreting effectiveness

Epilepsia, EarlyView.
This graphical abstract provides an overview of the content from this open‐label extension study of fenfluramine use in patients with Dravet syndrome or Lennox‐Gastaut syndrome. Abstract Objective Long‐term safety and global functioning are reported in patients with Dravet syndrome (DS) or Lennox–Gastaut syndrome (LGS) treated with fenfluramine in an ...
Antonio Gil‐Nagel, Kelly G. Knupp, Boudewijn Gunning, Domenica Immacolata Battaglia, Elizabeth A. Thiele, Ingrid E. Scheffer, An‐Sofie Schoonjans, Rima Nabbout, Nathalie Villeneuve, Kerstin Alexandra Klotz, Nicola Specchio, Rocio Sanchez‐Carpintero, Marta Zolnowska, Anne‐Liv Schulz, Lily Perrin, Najla Dickson, Mélanie Langlois, Amélie Lothe, Joseph Sullivan   +18 more
wiley   +1 more source

Noninvasive Evaluation of Portal Hypertension: Emerging Tools and Techniques

International Journal of Hepatology, 2012
Portal hypertension is the main cause of complications in patients with cirrhosis. However, evaluating the development and progression of portal hypertension represents a challenge for clinicians.
V. K. Snowdon, N. Guha, J. A. Fallowfield   +2 more
doaj   +1 more source

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis evaluating the efficacy and safety of fenfluramine in patients with Dravet syndrome stratified by age, number of previously attempted antiseizure medications, and SCN1A pathogenic variant status using data pooled from the three pivotal randomized controlled trials ...
Rima Nabbout, Joseph Sullivan, Stéphane Auvin, J. Helen Cross, Orrin Devinsky, Antonio Gil‐Nagel, Renzo Guerrini, Kelly G. Knupp, M. Scott Perry, Rocío Sánchez‐Carpintero, An‐Sofie Schoonjans, Ingrid E. Scheffer, Nicola Specchio, Adam Strzelczyk, James Wheless, Elaine C. Wirrell, Diego Morita, Patrick Healy, Mélanie Langlois, Amélie Lothe, Lieven Lagae   +20 more
wiley   +1 more source

A community of portal hypertension

, 2021
Portal hypertension is an important, if not the most important, factor affecting the clinical course of patients with cirrhosis, as it can predict the development of cirrhosis-related complications, such as variceal bleeding, ascites, and hepatic ...
Pavlides, Michael, Rockey, Don C, Huang, Yifei, Qi, Xiaolong   +3 more
core   +1 more source

Engineered molecular diagnostic strategies for hepatocellular carcinoma: Integrating flexible photonic barcodes, liquid biopsies, and AI‐enhanced sensing platforms

FlexMat, EarlyView.
Abstract Early diagnosis of hepatocellular carcinoma (HCC) remains challenging because conventional serum biomarkers, especially alpha‐fetoprotein (AFP), show limited sensitivity for early‐stage disease. Recent progress in engineered molecular diagnostics provides new opportunities to improve HCC detection through integrated material, molecular, and ...
Jingzhi Xue, Wanqi Yang, Xiaoyu Liu, Xuehui Chu, Wei Li, Jinglin Wang   +5 more
wiley   +1 more source

Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation [PDF]

, 2000
We tested the hypothesis that excessive portal venous supply of long-chain fatty acids to the liver contributes to the development of insulin resistance via activation of the hypothalamus-pituitary-adrenal axis (HPA axis) and sympathetic system.
Scheurink, AJW, Strubbe, JH, Keizer, Klaasjan,, Kuipers, Folkert,, Kuipers, F, Scheurink, Anton J.W.,, Benthem, L, Kuipers, F; id_orcid, Keizer, Klaas-Jan, Wiegman, Coen H.,, Strubbe, Jan H.,, Boer, Sietse F. de,, Steffens, Anton B.,, Steffens, AB, De Boer, SF, Benthem, Lambertus,, Wiegman, CH   +16 more
core