Results 1 to 10 of about 7,385,684 (193)

Volume and flow modulation strategies to mitigate post-hepatectomy liver failure [PDF]

Frontiers in Oncology, 2022
IntroductionPost hepatectomy liver failure is the most common cause of death following major hepatic resections with a perioperative mortality rate between 40% to 60%.
Richard Bell, Saleema Begum, Raj Prasad, Kojiro Taura, Bobby V. M. Dasari, Bobby V. M. Dasari   +5 more
doaj   +6 more sources

Biochemical and morphological responses to post-hepatectomy liver failure in rats [PDF]

Scientific Reports, 2023
The upper limit for partial hepatectomy (PH) in rats is 90%, which is associated with an increased risk of post-hepatectomy liver failure (PHLF), correlating with high mortality.
Andrea Lund, Kasper Jarlhelt Andersen, Michelle Meier, Marie Ingemann Pedersen, Anders Riegels Knudsen, Jakob Kirkegård, Frank Viborg Mortensen, Jens Randel Nyengaard   +7 more
doaj   +6 more sources

Early postoperative liver function parameters as predictors of post-hepatectomy liver failure [PDF]

Frontiers in Surgery
BackgroundPost-hepatectomy liver failure (PHLF) is a serious complication after liver resection and is associated with increased morbidity and mortality.
Schaima Abdelhadi, Mohamad El-Ahmar, Katharina Vedder, Mahmoud Halawa, Vanessa Orth, Maike Hermann, Meik Mönnichs, Georgi Vassilev, Christoph Reissfelder, Christoph Reissfelder, Flavius Sandra-Petrescu   +10 more
doaj   +5 more sources

The Impact of Post-Hepatectomy Liver Failure on Mortality: A Population-Based Study [PDF]

Scandinavian Journal of Gastroenterology, 2018
Post-hepatectomy liver failure (PHLF) is considered a main reason for death after major hepatectomy. The reported PHLF-related mortality differs largely and the data mainly originate from single centers.A retrospective, population-based register study was designed to evaluate the impact of PHLF on 90-day mortality after hepatectomy.All patients who ...
Magnus Rizell, Gert Lindell, Per Sandström   +2 more
exaly   +5 more sources

Rescue liver transplantation for post-hepatectomy liver failure- single center retrospective analysis [PDF]

BMC Surgery
Introduction Liver transplantation (LT) is a well-established method applied for the treatment of various liver diseases, including primary and secondary malignancies, as well as acute liver failure triggered by different mechanisms.
Łukasz Masior, Maciej Krasnodębski, Piotr Smoter, Marcin Morawski, Konrad Kobryń, Wacław Hołówko, Wojciech Figiel, Marek Krawczyk, Tadeusz Wróblewski, Michał Grąt   +9 more
doaj   +4 more sources

Critical Role of LSEC in Post-Hepatectomy Liver Regeneration and Failure [PDF]

International Journal of Molecular Sciences, 2021
Liver sinusoids are lined by liver sinusoidal endothelial cells (LSEC), which represent approximately 15 to 20% of the liver cells, but only 3% of the total liver volume. LSEC have unique functions, such as fluid filtration, blood vessel tone modulation, blood clotting, inflammatory cell recruitment, and metabolite and hormone trafficking.
Isabelle A Leclercq, Peter Stärkel, Maxime de Rudder   +2 more
exaly   +3 more sources

Influence of cytokines, circulating markers and growth factors on liver regeneration and post-hepatectomy liver failure: a systematic review and meta-analysis

Scientific Reports, 2021
The pathophysiology of post-hepatectomy liver failure is not entirely understood but is rooted in the disruption of normal hepatocyte regeneration and homeostasis.
Anastasia Murtha-Lemekhova, Juri Fuchs, Omid Ghamarnejad, Mohammedsadegh Nikdad, Pascal Probst, Katrin Hoffmann   +5 more
doaj   +1 more source

Systematic review of MARS treatment in post-hepatectomy liver failure [PDF]

HPB, 2020
Post-hepatectomy liver failure (PHLF) remains a serious complication after major liver resection with severe 90-day mortality. Molecular adsorbent recirculating system (MARS) is a potential treatment option in PHLF. This systematic review sought to analyze the experiences and results of MARS in PHLF.Following the PRISMA guidelines, a systematic ...
Ernesto, Sparrelid, Stefan, Gilg, Thomas M, van Gulik   +2 more
openaire   +4 more sources

Salvage Plasmapheresis for Post-hepatectomy Liver Failure [PDF]

Cureus, 2016
In the latest decades, an important change has been registered in liver surgery related to the progress of surgical techniques, critical care, and postoperative treatment, allowing a sharp decrease in mortality and morbidity. However, management of post-hepatectomy liver failure (PHLF) still remains a challenge and no supportive treatment has been ...
Inayat, Faisal, Hussain, Qulsoom, Tasleem, Syed H, Farooq, Sajid, Hurairah, Abu   +4 more
openaire   +2 more sources

Significance of predicted future liver remnant volume on liver failure risk after major hepatectomy: a case matched comparative study

Frontiers in Surgery, 2023
IntroductionFuture liver remnant volume (FLRV), a risk factor for liver failure (PHLF) after major hepatectomy (MH), is not routinely measured. This study aimed to evaluate the association between FLRV and PHLF.Patients and methodsAll patients undergoing
R. Piccus, K. Joshi, K. Joshi, J. Hodson, J. Hodson, D. Bartlett, N. Chatzizacharias, B. Dasari, B. Dasari, J. Isaac, R. Marudanayagam, D. F. Mirza, J. K. Roberts, J. K. Roberts, R. P. Sutcliffe, R. P. Sutcliffe   +15 more
doaj   +1 more source